Nanomaterials and nanomaterials-based drug delivery to promote cutaneous wound healing

T Liu, Y Lu, R Zhan, W Qian, G Luo - Advanced Drug Delivery Reviews, 2023 - Elsevier
Various factors could damage the structure and integrity of skin to cause wounds.
Nonhealing or chronic wounds seriously affect the well-being of patients and bring heavy …

Molecular bases of VEGFR-2-mediated physiological function and pathological role

X Wang, AM Bove, G Simone, B Ma - Frontiers in Cell and …, 2020 - frontiersin.org
The vascular endothelial growth factors (VEGFs) and their receptors (VEGFRs) play crucial
roles in vasculogenesis and angiogenesis. Angiogenesis is an important mechanism in …

[PDF][PDF] Vascular endothelial growth factor (VEGF)-key factor in normal and pathological angiogenesis

CS Melincovici, AB Boşca, S Şuşman… - Rom J Morphol …, 2018 - rjme.ro
Vascular endothelial growth factor (VEGF) represents a growth factor with important pro-
angiogenic activity, having a mitogenic and an anti-apoptotic effect on endothelial cells …

Reactive oxygen species in the tumor microenvironment: an overview

F Weinberg, N Ramnath, D Nagrath - Cancers, 2019 - mdpi.com
Reactive oxygen species (ROS) are important signaling molecules in cancer. The level of
ROS will determine physiological effects. While high levels of ROS can cause damage to …

Emerging roles of vascular cell adhesion molecule-1 (VCAM-1) in immunological disorders and cancer

DH Kong, YK Kim, MR Kim, JH Jang, S Lee - International journal of …, 2018 - mdpi.com
Tumor necrosis factor alpha (TNFα) is a pro-inflammatory cytokine that triggers the
expression of inflammatory molecules, including other cytokines and cell adhesion …

FAK in cancer: from mechanisms to therapeutic strategies

HH Chuang, YY Zhen, YC Tsai, CH Chuang… - International journal of …, 2022 - mdpi.com
Focal adhesion kinase (FAK), a non-receptor tyrosine kinase, is overexpressed and
activated in many cancer types. FAK regulates diverse cellular processes, including growth …

A conduit to metastasis: circulating tumor cell biology

DS Micalizzi, S Maheswaran… - Genes & …, 2017 - genesdev.cshlp.org
Advances in the enrichment and analysis of rare cells from the bloodstream have allowed for
detection and characterization of circulating tumor cells (CTCs) from patients with cancer …

Pathophysiology of chronic subdural haematoma: inflammation, angiogenesis and implications for pharmacotherapy

E Edlmann, S Giorgi-Coll, PC Whitfield… - Journal of …, 2017 - Springer
Chronic subdural haematoma (CSDH) is an encapsulated collection of blood and fluid on
the surface of the brain. Historically considered a result of head trauma, recent evidence …

The role of the VEGF family in coronary heart disease

Y Zhou, X Zhu, H Cui, J Shi, G Yuan, S Shi… - Frontiers in …, 2021 - frontiersin.org
The vascular endothelial growth factor (VEGF) family, the regulator of blood and lymphatic
vessels, is mostly investigated in the tumor and ophthalmic field. However, the functions it …

The roles of vascular endothelial growth factor in bone repair and regeneration

K Hu, BR Olsen - Bone, 2016 - Elsevier
Vascular endothelial growth factor-A (VEGF) is one of the most important growth factors for
regulation of vascular development and angiogenesis. Since bone is a highly vascularized …