C3 glomerulopathies: dense deposit disease and C3 glomerulonephritis

C Ponticelli, M Calatroni, G Moroni - Frontiers in Medicine, 2023 - frontiersin.org
Dense deposit disease (DDD) and C3 glomerulonephritis (C3GN) are types of
membranoproliferative glomerulonephritis classified as C3 glomerulopathies. These …

Utility of C4d Immunohistochemistry as an Adjunct Stain in Diagnostic Renal Pathology of Glomerular Diseases

I Pradeep, BH Srinivas - International Journal of Surgical …, 2024 - journals.sagepub.com
C4d is a byproduct of the activation of the classic and lectin complement pathways. Being
routinely used as a marker for antibody-mediated rejection, the significance of C4d in native …

The C3 conundrum

M Lean, B Chacko - Internal medicine journal, 2023 - Wiley Online Library
A 62‐year‐old man with nephritic syndrome underwent a kidney biopsy which revealed a
C3 dominant pattern on immunofluorescence. A diagnosis of C3 glomerulopathy (C3G) was …

The diagnostic significance of C4d deposits, as an immunohistochemical proof of complement activation, in kidney glomerular pathologies and kidney transplantation.

S Hresko, M Madarova, M Dobosova… - Bratislava Medical …, 2024 - search.ebscohost.com
C4d, a split product of C4 activation in classical and lectin pathways of the complement
system activation, has been regarded as a footprint of tissue damage in antibody-mediated …