Exosomes─ nature's lipid nanoparticles, a rising star in drug delivery and diagnostics
Exosomes are a subgroup of nanosized extracellular vesicles enclosed by a lipid bilayer
membrane and secreted by most eukaryotic cells. They represent a route of intercellular …
membrane and secreted by most eukaryotic cells. They represent a route of intercellular …
[HTML][HTML] Bone remodeling: an operational process ensuring survival and bone mechanical competence
S Bolamperti, I Villa, A Rubinacci - Bone Research, 2022 - nature.com
Bone remodeling replaces old and damaged bone with new bone through a sequence of
cellular events occurring on the same surface without any change in bone shape. It was …
cellular events occurring on the same surface without any change in bone shape. It was …
Bone‐Targeted Exosomes: Strategies and Applications
J Wang, X Li, S Wang, J Cui, X Ren… - Advanced Healthcare …, 2023 - Wiley Online Library
As the global population ages, bone‐related diseases have increasingly become a major
social problem threatening human health. Exosomes, as natural cell products, have been …
social problem threatening human health. Exosomes, as natural cell products, have been …
[HTML][HTML] Exosome-derived microRNAs of human milk and their effects on infant health and development
BC Melnik, W Stremmel, R Weiskirchen, SM John… - Biomolecules, 2021 - mdpi.com
Multiple biologically active components of human milk support infant growth, health and
development. Milk provides a wide spectrum of mammary epithelial cell-derived …
development. Milk provides a wide spectrum of mammary epithelial cell-derived …
[HTML][HTML] Co–culture systems of osteoblasts and osteoclasts: Simulating in vitro bone remodeling in regenerative approaches
G Borciani, G Montalbano, N Baldini, G Cerqueni… - Acta biomaterialia, 2020 - Elsevier
Bone is an extremely dynamic tissue, undergoing continuous remodeling for its whole
lifetime, but its regeneration or augmentation due to bone loss or defects are not always …
lifetime, but its regeneration or augmentation due to bone loss or defects are not always …
Engineered extracellular vesicles for bone therapy
Extracellular vesicles, which are secreted by living cells and play a critical role in cellular
communication, have emerged as a promising cell-free strategy in the treatment of many …
communication, have emerged as a promising cell-free strategy in the treatment of many …
[HTML][HTML] In vitro Models of Bone Remodelling and Associated Disorders
Disruption of bone remodelling by diseases such as osteoporosis results in an imbalance
between bone formation by osteoblasts and resorption by osteoclasts. Research into these …
between bone formation by osteoblasts and resorption by osteoclasts. Research into these …
[HTML][HTML] Human oral stem cells, biomaterials and extracellular vesicles: a promising tool in bone tissue repair
O Trubiani, GD Marconi, SD Pierdomenico… - International Journal of …, 2019 - mdpi.com
Tissue engineering and/or regenerative medicine are fields of life science exploiting both
engineering and biological fundamentals to originate new tissues and organs and to induce …
engineering and biological fundamentals to originate new tissues and organs and to induce …
microRNA-935-modified bone marrow mesenchymal stem cells-derived exosomes enhance osteoblast proliferation and differentiation in osteoporotic rats
Y Zhang, X Cao, P Li, Y Fan, L Zhang, X Ma, R Sun… - Life sciences, 2021 - Elsevier
Aims The involvement of several microRNAs (miRNAs) in osteogenic differentiation has
been indicated recently. Also, exosomes, derived from different cells, could shuttle specific …
been indicated recently. Also, exosomes, derived from different cells, could shuttle specific …