[HTML][HTML] Neurotoxicity in snakebite—the limits of our knowledge

UK Ranawaka, DG Lalloo… - PLoS neglected tropical …, 2013 - journals.plos.org
Snakebite is classified by the WHO as a neglected tropical disease. Envenoming is a
significant public health problem in tropical and subtropical regions. Neurotoxicity is a key …

Neuroinflammation: An overview of neurodegenerative and metabolic diseases and of biotechnological studies

AP de Araújo Boleti, TM de Oliveira Flores… - Neurochemistry …, 2020 - Elsevier
Neuroinflammation is an important factor contributing to cognitive impairment and
neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD) …

Phylovenomics of Daboia russelii across the Indian subcontinent. Bioactivities and comparative in vivo neutralization and in vitro third-generation antivenomics of …

D Pla, L Sanz, S Quesada-Bernat, M Villalta, J Baal… - Journal of …, 2019 - Elsevier
Russell's viper (Daboia russelii) is, together with Naja naja, Bungarus caeruleus and Echis
carinatus, a member of the medically important 'Big Four'species responsible for causing a …

Immune response towards snake venoms

G León, L Sánchez, A Hernández… - … & Allergy-Drug …, 2011 - ingentaconnect.com
The immune response involves a complex repertoire of innate and adaptive responses to
foreign agents in the organism. The present review focuses on the immune response to …

Functional venomics of the Sri Lankan Russell's viper (Daboia russelii) and its toxinological correlations

NH Tan, SY Fung, KY Tan, MKK Yap… - Journal of …, 2015 - Elsevier
The venom proteome (venomics) of the Sri Lankan Daboia russelii was elucidated using 1D
SDS PAGE nano-ESI-LCMS/MS shotgun proteomics. A total of 41 different venom proteins …

Proteomic analysis reveals geographic variation in venom composition of Russell's Viper in the Indian subcontinent: Implications for clinical manifestations post …

B Kalita, SP Mackessy… - Expert review of proteomics, 2018 - Taylor & Francis
ABSTRACT Introduction: The Russell's Viper (RV)(Daboia russelii), a category I medically
important snake, is responsible for a significant level of morbidity and mortality in the Indian …

Proteomics, functional characterization and antivenom neutralization of the venom of Pakistani Russell's viper (Daboia russelii) from the wild

T Faisal, KY Tan, SM Sim, N Quraishi, NH Tan… - Journal of …, 2018 - Elsevier
The venom proteome of wild Pakistani Russell's viper (Daboia russelii) was investigated
through nano-ESI-LCMS/MS of the reverse-phase HPLC fractions. A total of 54 venom …

[HTML][HTML] Animal toxins as therapeutic tools to treat neurodegenerative diseases

JM De Souza, BDC Goncalves, MV Gomez… - Frontiers in …, 2018 - frontiersin.org
Neurodegenerative diseases affect millions of individuals worldwide. So far, no disease-
modifying drug is available to treat patients, making the search for effective drugs an urgent …

[HTML][HTML] In Vitro Efficacy of Antivenom and Varespladib in Neutralising Chinese Russell's Viper (Daboia siamensis) Venom Toxicity

M Lay, Q Liang, GK Isbister, WC Hodgson - Toxins, 2023 - mdpi.com
The venom of the Russell's viper (Daboia siamensis) contains neurotoxic and myotoxic
phospholipase A2 toxins which can cause irreversible damage to motor nerve terminals …

[HTML][HTML] Proteomics, toxicity and antivenom neutralization of Sri Lankan and Indian Russell's viper (Daboia russelii) venoms

T Faisal, KY Tan, NH Tan, SM Sim… - Journal of Venomous …, 2021 - SciELO Brasil
Abstract Background: The western Russell's viper (Daboia russelii) is widely distributed in
South Asia, and geographical venom variation is anticipated among distant populations …