An individualized innovative disease management is of great importance for people with
multiple sclerosis (pwMS) to cope with the complexity of this chronic, multidimensional …

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous
system (CNS) where immunopathology is thought to be mediated by myelin-reactive CD4+ T …

Increased reactive oxygen species production and oxidative stress have been implicated in
the pathogenesis of numerous neurodegenerative conditions including among others …

Since its discovery in inflammatory macrophages, itaconate has attracted much attention
due to its antimicrobial and immunomodulatory activity,–. However, instead of investigating …

A proper clinical evaluation of patients with Multiple Sclerosis (MS) is of great importance to
detect MS progression. It provides important data for physicians on their daily practice as …

The coronavirus disease 2019 (COVID-19) pandemic is caused by a novel severe acute
respiratory syndrome (SARS)-like coronavirus (SARS-CoV-2). Here, we review the …

Neurodegenerative diseases (NDs) represents debilitating conditions characterized by
degeneration of neuronal cells in specific brain areas, causing disability and death in …

Covering: up to 2020 The transcription factor NRF2 is one of the body's major defense
mechanisms, driving transcription of> 300 antioxidant response element (ARE)-regulated …

The cardioprotective effects of dietary nitrate from beetroot in healthy and hypertensive
individuals are undeniable and irrefutable. Nitrate and nitrate-derived nitrite are precursors …

NRF2 is a basic leucine zipper (bZip) transcription factor that is the master regulator of redox
homeostasis. Under basal conditions, the cellular level of NRF2 is low due to a …