Autologous keratinocyte cultures and combinations of scaffolds, different cell types, solutions
of macromolecules, or growth factors have contributed to the resurfacing of burns and large …

Over 100 million patients acquire scars in the industrialized world each year, primarily as a
result of elective operations. Although undefined, the global incidence of scarring is even …

Fibroblasts are an essential cell population for human skin architecture and function. While
fibroblast heterogeneity is well established, this phenomenon has not been analyzed …

The skin barrier is the body's first line of defence against environmental assaults, and is
maintained by epithelial stem cells (EpSCs). Despite the vulnerability of EpSCs to …

The murine epidermis with its hair follicles represents an invaluable model system for tissue
regeneration and stem cell research. Here we used single-cell RNA-sequencing to reveal …

Oropharyngeal candidiasis (OPC; thrush) is an opportunistic infection caused by the
commensal fungus Candida albicans. Interleukin-17 (IL-17) and IL-22 are cytokines …

Purpose This review will discuss the role of vitamin D and calcium signaling in the epidermal
wound response with particular focus on the stem cells of the epidermis and hair follicle that …

Type XVII collagen (COL17) is a transmembrane protein located at the epidermal basement
membrane zone. COL17 deficiency results in premature hair aging phenotypes and in …

Aging human tissues, such as sun-exposed epidermis, accumulate a high burden of
progenitor cells that carry oncogenic mutations. However, most progenitors carrying such …

The skin is the largest organ in the body and plays multiple essential roles ranging from
regulating temperature, preventing infection and ultimately defining who we are physically. It …