Ischaemic strokes have traditionally been classified according to the TOAST criteria, in
which strokes with unclear aetiology are classified as cryptogenic strokes. However, the …

Summary Globally, up to 1· 5 million individuals with ischaemic stroke or transient ischaemic
attack can be newly diagnosed with atrial fibrillation per year. In the past decade, evidence …

For example, a treatment that reduces mortality from severe COVID-19 saves some patients
who would otherwise have died, but others may die despite treatment, others may survive …

Randomized clinical trials (RCT) represent the cornerstone of evidence-based medicine but
are resource-intensive. We propose and evaluate a machine learning (ML) strategy of …

Patent foramen ovale (PFO) is frequently identified in young patients with ischemic stroke.
Randomized controlled trials provide robust evidence supporting PFO closure in selected …

Ischaemic or haemorrhagic perioperative stroke (that is, stroke occurring during or within 30
days following surgery) can be a devastating complication following surgery. Incidence is …

Importance The Patent Foramen Ovale (PFO)–Associated Stroke Causal Likelihood
classification system combines information regarding noncardiac patient features (vascular …

Background: The main randomized trials evaluating patent foramen ovale (PFO) closure
after a presumed PFO-associated stroke excluded patients older than 60 years. We aimed to …

Background Stroke is an acute disorder and dysfunction of the focal neurological system that
has long been recognized as one of the leading causes of death and severe disability in …

Objective Arterial aneurysms are life-threatening but usually asymptomatic before requiring
hospitalization. Oculomics of retinal vascular features (RVFs) extracted from retinal fundus …