Soft tissue defects are a common clinical challenge mostly caused by trauma, congenital
anomalies and oncological surgery. Current soft tissue reconstruction options include …

Abstract Three‐dimensional (3D) cell cultures represent the spontaneous state of stem cells
with specific gene and protein molecular expression that are more alike the in vivo condition …

Overcoming the problem of vascularization remains the main challenge in the field of tissue
engineering. As three-dimensional (3D) bioprinting is the rising technique for the fabrication …

Numerous methods have been reported for the fabrication of 3D multi-cellular spheroids and
their use in stem cell culture. Current methods typically relying on the self-assembly of …

Wound healing is a complex physiological process that is controlled by a well-orchestrated
cascade of interdependent biochemical and cellular events, which has spurred the …

The encapsulation of bevacizumab (BVZ), angiogenesis inhibitor antibody, into nanocarriers
is explored aiming at enhancing its efficacy in colorectal cancer (CRC) treatment while …

Tissue engineering offers a promising strategy to restore injuries resulting from trauma,
infection, tumor resection, or other diseases. In spite of significant progress, the field faces a …

Mesenchymal stromal cells (MSCs) are under investigation for wound healing and tissue
regeneration due to their potent secretome. Compared to monodisperse cells, MSC …

Mesenchymal stem cells (MSCs) have drawn worldwide attention of scientists and clinicians
due to their ability to differentiate into other cell lineages, secrete paracrine factors, modulate …

Radiation therapy (RT) is a typical treatment for head and neck cancers. Generally,
prolonged irradiation of the esophagus causes esophageal fibrosis due to increased …