A proposal for a serology-based approach to membranous nephropathy

AS De Vriese, RJ Glassock, KA Nath… - Journal of the …, 2017 - journals.lww.com
Primary membranous nephropathy (MN) is an autoimmune disease mainly caused by
autoantibodies against the recently discovered podocyte antigens: the M-type …

[HTML][HTML] Membranous nephropathy: integrating basic science into improved clinical management

DC Cattran, PE Brenchley - Kidney international, 2017 - Elsevier
Idiopathic membranous nephropathy (INM) remains a common cause of the nephrotic
syndrome in adults. The autoimmune nature of IMN was clearly delineated in 2009 with the …

[HTML][HTML] The anti-PLA2R antibody in membranous nephropathy: what we know and what remains a decade after its discovery

AE van de Logt, M Fresquet, JF Wetzels, P Brenchley - Kidney international, 2019 - Elsevier
The discovery in 2009 of the M-type phospholipase A2 receptor (PLA2R) as the primary
target in membranous nephropathy (MN) greatly advanced basic and clinical research …

PLA2R and THSD7A: disparate paths to the same disease?

LH Beck Jr - Journal of the American Society of Nephrology, 2017 - journals.lww.com
The phospholipase A2 receptor (PLA2R) and thrombospondin type-1 domain-containing 7A
(THSD7A) are the two major autoantigens in primary membranous nephropathy (MN), and …

Membranous nephropathy.

C Ponticelli, P Passerini - Treatment of Primary …, 1997 - books.google.com
Primary membranous nephropathy (MN) is an auto-immune glomerular disease which is
characterized histologically by uniform thickening of the glomerular capillary due to the …

[HTML][HTML] Mechanisms of primary membranous nephropathy

Y Gu, H Xu, D Tang - Biomolecules, 2021 - mdpi.com
Membranous nephropathy (MN) is an autoimmune disease of the kidney glomerulus and
one of the leading causes of nephrotic syndrome. The disease exhibits heterogenous …

Molecular pathogenesis of membranous nephropathy

P Ronco, H Debiec - Annual Review of Pathology: Mechanisms …, 2020 - annualreviews.org
Membranous nephropathy is a noninflammatory autoimmune disease of the kidney
glomerulus, characterized by the formation of immune deposits, complement-mediated …

Membranous nephropathy: approaches to treatment

AS Bomback, FC Fervenza - American journal of nephrology, 2018 - karger.com
Background: Membranous nephropathy (MN) is a common cause of nephrotic syndrome in
adults. This review focuses on mechanisms involved in the pathogenesis of MN and …

HLA and kidney disease: from associations to mechanisms

KJ Robson, JD Ooi, SR Holdsworth… - Nature Reviews …, 2018 - nature.com
Since the first association between HLA and diseases of native kidneys was described
almost 50 years ago, technological and conceptual advances in HLA biology and typing …

[HTML][HTML] GWAS-based discoveries in IgA nephropathy, membranous nephropathy, and steroid-sensitive nephrotic syndrome

E Sanchez-Rodriguez, CT Southard… - Clinical Journal of the …, 2021 - journals.lww.com
Over the past decade, genome-wide association studies (GWAS) have emerged as a
powerful tool to understand the genetic basis of complex traits in humans. The GWAS …