Interplay between RAS and opioids: opening the Pandora of complexities

A Bali, PK Randhawa, AS Jaggi - Neuropeptides, 2014 - Elsevier
Angiotensin and endogenous opioids are important bioactive neuropeptides, which are
widely distributed in the brain and peripheral regions to produce diverse biological and …

Angiotensin converting enzyme inhibition: Unique and effective therapy for hypertension and congestive heart failure

R DiBianco - Postgraduate Medicine, 1985 - Taylor & Francis
Preview Because it affords physicians the only known mechanism that blocks the activity of
the renin-angiotensin-aldosterone system, angiotensin converting enzyme (ACE) inhibition …

Buprenorphine: a new pharmacotherapy for opioid addictions treatment

C Stock, JH Shum - Journal of pain & palliative care …, 2004 - Taylor & Francis
The federal Drug Abuse Treatment Act 2000 (DATA) opened a window of opportunity for
patients with the disease of addiction by providing increased access to options for treatment …

Angiotensin converting enzyme inhibitor intoxication: naloxone to the rescue? Naloxone for ACE inhibitor intoxication

M Robert, D De Bels, M Chaumont, PM Honoré… - The American Journal of …, 2019 - Elsevier
We report here the case of a patient with perindopril intoxication inducing severe
bradycardia together with a profound hypotension. Initiation of a naloxone infusion …

Small-dose naloxone combined with epinephrine improves the resuscitation of cardiopulmonary arrest

Y Wang, L Gao, L Meng - The American journal of emergency medicine, 2008 - Elsevier
OBJECTIVES: To investigate if naloxone combined with epinephrine can increase the
resuscitation rate in cardiac arrest rat models induced by asphyxia. METHODS: Twenty-four …

Ace inhibitors: a safe option for hypertension and congestive heart failure

P Amadio Jr, PB Amadio, DM Cummings - Postgraduate Medicine, 1990 - Taylor & Francis
Preview ACE inhibitors are apparently both safe and effective for antihypertensive therapy
and do not have a negative impact on quality of life. Compliance is enhanced by ease of …

Inhibitory regulation by co-released peptides of catecholamine secretion by the canine adrenal medulla.

JA Critchley, MR MacLean, A Ungar - British journal of …, 1988 - ncbi.nlm.nih.gov
We have stimulated the peripheral end of the cut left splanchnic nerve in anaesthetized dogs
while collecting the venous effluent of the left adrenal gland for catecholamine estimation. 2 …

Naloxone does not antagonize the antihypertensive effect of chronic captopril therapy in hypertensive patients

GP Bernini, AR Lucarini, MS Vivaldi… - … drugs and therapy, 1989 - Springer
It has been reported that naloxone, an opiate receptor antagonist, blunts the hypotensive
effect of captopril in normotensives. However, our previous data did not show any interaction …

The influence of captopril and naloxone on the Valsalva manoeuvre and systolic time intervals in healthy volunteers

JP Richter, DK Sommers… - Clinical and experimental …, 1994 - Wiley Online Library
The aim of the study was to ascertain whether the inhibition of the sympathetic nervous
system by angiotensin‐converting enzyme (ACE) inhibitors is mediated by endogenous …

Captopril and opiate antagonism in essential hypertension.

AA Ajayi, PC Rubin, JL Reid - British journal of clinical …, 1986 - Wiley Online Library
Six patients maintained on 50‐100 mg captopril, for 2‐25 months, were administered
captopril 50 mg orally, together with either naloxone or 0.9% saline vehicle (placebo) given …