[HTML][HTML] Role of extracellular vesicles as potential diagnostic and/or therapeutic biomarkers in chronic cardiovascular diseases

JL Martin-Ventura, C Roncal, J Orbe… - Frontiers in cell and …, 2022 - frontiersin.org
Cardiovascular diseases (CVDs) are the first cause of death worldwide. In recent years,
there has been great interest in the analysis of extracellular vesicles (EVs), including …

[HTML][HTML] The important role of endothelium and extracellular vesicles in the cellular mechanism of aortic aneurysm formation

K Mikołajczyk, D Spyt, W Zielińska, A Żuryń… - International journal of …, 2021 - mdpi.com
Homeostasis is a fundamental property of biological systems consisting of the ability to
maintain a dynamic balance of the environment of biochemical processes. The action of …

Galectin-1 prevents pathological vascular remodeling in atherosclerosis and abdominal aortic aneurysm

R Roldán-Montero, JM Pérez-Sáez, I Cerro-Pardo… - Science …, 2022 - science.org
Pathological vascular remodeling is the underlying cause of atherosclerosis and abdominal
aortic aneurysm (AAA). Here, we analyzed the role of galectin-1 (Gal-1), a β-galactoside …

[HTML][HTML] Circulating biomarkers for the prediction of abdominal aortic aneurysm growth

P Nana, K Dakis, A Brodis, K Spanos… - Journal of Clinical …, 2021 - mdpi.com
Background: Abdominal aortic aneurysm represents a distinct group of vascular lesions, in
terms of surveillance and treatment. Screening and follow-up of patients via duplex …

[HTML][HTML] Protection of diabetes in aortic abdominal aneurysm: Are antidiabetics the real effectors?

B Picatoste, I Cerro-Pardo, LM Blanco-Colio… - Frontiers in …, 2023 - frontiersin.org
Aortic aneurysms, including abdominal aortic aneurysms (AAAs), is the second most
prevalent aortic disease and represents an important cause of death worldwide. AAA is a …

[HTML][HTML] Rolipram prevents the formation of abdominal aortic aneurysm (AAA) in mice: PDE4B as a target in AAA

S Varona, L Puertas, M Galán, M Orriols, L Cañes… - Antioxidants, 2021 - mdpi.com
Abdominal aortic aneurysm (AAA) is a common life-threatening condition characterized by
exacerbated inflammation and the generation of reactive oxygen species. Pharmacological …

[HTML][HTML] APOA1 oxidation is associated to dysfunctional high-density lipoproteins in human abdominal aortic aneurysm

D Martínez-López, E Camafeita, L Cedó… - …, 2019 - thelancet.com
Background High-density lipoproteins (HDL) are a complex mixture of lipids and proteins
with vasculoprotective properties. However, HDL components could suffer post-translational …

[HTML][HTML] PDE4 Phosphodiesterases in Cardiovascular Diseases: Key Pathophysiological Players and Potential Therapeutic Targets

L Puertas-Umbert, J Alonso, L Hove-Madsen… - International Journal of …, 2023 - mdpi.com
3′, 5′-cyclic adenosine monophosphate (cAMP) is a second messenger critically involved
in the control of a myriad of processes with significant implications for vascular and cardiac …

[HTML][HTML] Emerging landscape of circFNDC3B and its role in human malignancies

K Sun, H Yao, P Zhang, Y Sun, J Ma, Q Xia - Frontiers in Oncology, 2023 - frontiersin.org
In recent years, more attention has been paid to expanding the abundance of Circular RNAs
(circRNAs), while the circRNAs that have been found to have significant functions have not …

[HTML][HTML] Blood immunological profile of abdominal aortic aneurysm based on autoimmune injury

H Huanggu, D Yang, Y Zheng - Autoimmunity Reviews, 2023 - Elsevier
Abdominal aortic aneurysm (AAA) occupies a large part of aorta aneurysm, and if there's no
timely intervention or treatment, the risks of rupture and death would rise sharply. With the …