Aging is a complex process indicated by low energy levels, declined physiological activity,
stress induced loss of homeostasis leading to the risk of diseases and mortality. Recent …

The current increase in lifespan without an equivalent increase in healthspan poses a grave
challenge to the healthcare system and a severe burden on society. However, some …

Comparative oncology is an understudied field of science. We are far from understanding
the key mechanisms behind Peto's paradox, ie understanding how long-lived and large …

Within primates, the great apes are outliers both in terms of body size and lifespan, since
they include the largest and longest-lived species in the order. Yet, the molecular bases …

Comparative studies of cancer‐related genes not only provide novel information about their
evolution and function but also an understanding of cancer as a driving force in biological …

Environmental factors can cause cancer in both wild animals and humans. In ecological
settings, genetic variation and natural selection can sometimes produce resilience to the …

Few fishes have evolved elevated body temperatures compared with ambient temperatures,
and only in opah (Lampris spp) is the entire body affected. To understand the molecular …

Natural selection has shaped a wide range of lifespans across mammals, with a few long-
lived species showing negligible signs of ageing. Approaches used to elucidate the genetic …

The red sea urchin (Mesocentrotus franciscanus) is one of the Earth's longest-living animals,
reported to live more than 100 years with indeterminate growth, life-long reproduction, and …

Lifespan is a life-history trait that undergoes natural selection. Telomeres are hallmarks of
aging, and shortening rate predicts species lifespan, making telomere maintenance …