Candida albicans at Host Barrier Sites: Pattern Recognition Receptors and Beyond
M Swidergall - Pathogens, 2019 - mdpi.com
Over the last decades, fungal infections have emerged as a growing threat to human health.
Although the human body is at potential risk, various body sites host several commensal …
Although the human body is at potential risk, various body sites host several commensal …
Secreted Aspartic Protease Cleavage of Candida albicans Msb2 Activates Cek1 MAPK Signaling Affecting Biofilm Formation and Oropharyngeal Candidiasis
Perception of external stimuli and generation of an appropriate response are crucial for host
colonization by pathogens. In pathogenic fungi, mitogen activated protein kinase (MAPK) …
colonization by pathogens. In pathogenic fungi, mitogen activated protein kinase (MAPK) …
Mucin glycans: A target for cancer therapy
L Sun, Y Zhang, W Li, J Zhang, Y Zhang - Molecules, 2023 - mdpi.com
Mucin glycans are an important component of the mucus barrier and a vital defence against
physical and chemical damage as well as pathogens. There are 20 mucins in the human …
physical and chemical damage as well as pathogens. There are 20 mucins in the human …
A genome-wide screen of deletion mutants in the filamentous Saccharomyces cerevisiae background identifies ergosterol as a direct trigger of macrophage pyroptosis
Phagocytic cells such as macrophages play an important role in the host defense
mechanisms mounted in response to the common human fungal pathogen Candida …
mechanisms mounted in response to the common human fungal pathogen Candida …
Nutrient and stress sensing in pathogenic yeasts
JC Rutherford, YS Bahn, B Van Den Berg… - Frontiers in …, 2019 - frontiersin.org
More than 1.5 million fungal species are estimated to live in vastly different environmental
niches. Despite each unique host environment, fungal cells sense certain fundamentally …
niches. Despite each unique host environment, fungal cells sense certain fundamentally …
Flor yeast: new perspectives beyond wine aging
The most important dogma in white-wine production is the preservation of the wine aroma
and the limitation of the oxidative action of oxygen. In contrast, the aging of Sherry and …
and the limitation of the oxidative action of oxygen. In contrast, the aging of Sherry and …
Profiling the secretome and extracellular proteome of the potato late blight pathogen Phytophthora infestans
Oomycetes are filamentous organisms that cause notorious diseases, several of which have
a high economic impact. Well known is Phytophthora infestans, the causal agent of potato …
a high economic impact. Well known is Phytophthora infestans, the causal agent of potato …
Beyond the wall: Candida albicans secret(e)s to survive
AG Sorgo, CJ Heilmann, S Brul… - FEMS microbiology …, 2013 - academic.oup.com
The opportunistic fungal pathogen Candida albicans occupies various niches of the human
body such as the skin and the mucosal surfaces of the gastrointestinal and urogenital tracts …
body such as the skin and the mucosal surfaces of the gastrointestinal and urogenital tracts …
An acquired mechanism of antifungal drug resistance simultaneously enables Candida albicans to escape from intrinsic host defenses
IAI Hampe, J Friedman, M Edgerton… - PLoS …, 2017 - journals.plos.org
The opportunistic fungal pathogen Candida albicans frequently produces genetically altered
variants to adapt to environmental changes and new host niches in the course of its life-long …
variants to adapt to environmental changes and new host niches in the course of its life-long …
Fungal resilience and host–pathogen interactions: future perspectives and opportunities
AJP Brown - Parasite Immunology, 2023 - Wiley Online Library
We are constantly exposed to the threat of fungal infection. The outcome—clearance,
commensalism or infection—depends largely on the ability of our innate immune defences …
commensalism or infection—depends largely on the ability of our innate immune defences …