Abstract Bone morphogenetic protein 9 (BMP9) is a circulating factor produced by hepatic
stellate cells that plays a critical role in vascular quiescence through its endothelial receptor …

Men have higher blood pressure than women through much of life regardless of race and
ethnicity. This is a robust and highly conserved sex difference that it is also observed across …

The metabolic syndrome is an important public health concern that predisposes individuals
to the development of cardiovascular disease and/or Type 2 diabetes. The fructose-fed rat is …

Context Fructose-rich beverages such as sugar-sweetened soda and orange juice can
increase serum uric acid levels and, thus, the risk of gout, but prospective data on the …

Background: Excessive fructose intake causes metabolic syndrome in animals and can be
partially prevented by lowering the uric acid level. We tested the hypothesis that fructose …

Objective Sugar‐sweetened soft drinks contain large amounts of fructose, which may
significantly increase serum uric acid levels and the risk of gout. Our objective was to …

Type 2 diabetes mellitus (T2DM) is strongly associated with obesity in most, but not all,
ethnic groups, suggesting important ethnic differences in disease susceptibility. Although it …

Abstract FOXO1A and FOXO3A are two members of the FoxO family. FOXO3A has recently
been linked to human longevity in Japanese, German and Italian populations. Here we …

Objective: The aim of this study was to assess the suitability of A/J and C57BL/6J mice of
both sexes as models of some components of the human metabolic syndrome (MetS) under …

Fructose induces metabolic syndrome in rats; but studies have been criticized for using high
concentrations of fructose that are not physiologic, for using only pure fructose, and for not …