Endothelin-1 modulates angiotensin II in the development of hypertension in fructose-fed rats

LT Tran, KM MacLeod, JH McNeill - Molecular and cellular biochemistry, 2009 - Springer
Two of the most potent vasoconstrictors, endothelin-1 (ET-1) and angiotensin II (Ang II), are
upregulated in fructose hypertensive rats. It is unknown whether an interrelationship exists …

Maternal fructose induces gender-dependent changes in both LXRα promoter methylation and cholesterol metabolism in progeny

S Rodrigo, E Fauste, M de la Cuesta… - The Journal of …, 2018 - Elsevier
Fructose consumption from added sugars correlates with the epidemic rise in obesity,
metabolic syndrome and cardiovascular diseases. However, consumption of beverages …

Effects of dietary fat, NaCl, and fructose on renal sodium and water transporter abundances and systemic blood pressure

J Song, X Hu, M Shi, MA Knepper… - American Journal of …, 2004 - journals.physiology.org
Dietary fructose, NaCl, and/or saturated fat have been correlated with mean arterial pressure
(MAP) rises in sensitive strains of rats. Dysregulation of sodium and/or water reabsorption by …

[HTML][HTML] The effects of four hypocaloric diets containing different levels of sucrose or high fructose corn syrup on weight loss and related parameters

J Lowndes, D Kawiecki, S Pardo, V Nguyen… - Nutrition Journal, 2012 - Springer
Background The replacement of sucrose with HFCS in food products has been suggested
as playing a role in the development of obesity as a public health issue. The objective of this …

Elevated dietary sugar and the heart: experimental models and myocardial remodeling

KM Mellor, RH Ritchie, AJ Davidoff… - Canadian journal of …, 2010 - cdnsciencepub.com
A dramatic rise in the prevalence of insulin resistance has been paralleled by increasing
dietary consumption of sugar. The use of added sweeteners containing fructose (sucrose …

Comparison of the effects of sulforaphane and pioglitazone on insulin resistance and associated dyslipidemia, hepatosteatosis, and endothelial dysfunction in fructose …

NM Shawky, GSG Shehatou, GM Suddek… - Environmental …, 2019 - Elsevier
The purpose of this work was to compare the influences of sulforaphane (SFN) to those of
the standard insulin sensitizer pioglitazone (PIO) on high fructose diet (HFrD)-induced …

Levocetirizine ameliorates high fructose diet-induced insulin resistance, vascular dysfunction and hepatic steatosis in rats

NM Shawky, GSG Shehatou, MA Rahim… - European journal of …, 2014 - Elsevier
This study investigates the possible protective effects of levocetirizine against fructose-
induced insulin resistance, hepatic steatosis and vascular dysfunction, in comparison to …

Relationship among hyperinsulinemia, insulin resistance, and hypertension is dependent on sex

DM Galipeau, L Yao… - American Journal of …, 2002 - journals.physiology.org
Hyperinsulinemia and insulin resistance have been linked to hypertension; however, the
influence of sex on this relationship has not been well studied. The purpose of this …

Quercetin administration post‐weaning attenuates high‐fructose, high‐cholesterol diet‐induced hepatic steatosis in growing, female, Sprague Dawley rat pups

J Donaldson, M Ngema, P Nkomozepi… - Journal of the …, 2019 - Wiley Online Library
BACKGROUND Fructose and cholesterol‐rich diets have been implicated in the upsurge of
metabolic syndrome (MetS). Phytochemicals are being explored as alternatives for the …

Postnatal maternal separation modifies the response to an obesogenic diet in adulthood in rats

L Paternain, E Martisova, FI Milagro… - Disease Models & …, 2012 - journals.biologists.com
An early-life adverse environment has been implicated in the susceptibility to different
diseases in adulthood, such as mental disorders, diabetes and obesity. We analyzed the …