The consequences of excessive fructose intake extend beyond those of metabolic disorder
to changes in emotional regulation and cognitive function. Long-term consumption of …

Introduction: The cardiovascular renin–angiotensin system (RAS) could be affected by
gender and dietary regime. We hypothesized that male rats will be more susceptible to …

We investigated the antihypertensive effect of a methanol extract (ME) of fenugreek seeds
and its methanol fraction (MF) in deoxycorticosterone acetate (DOCA)-salt-induced and …

High fructose intake has been associated with increased incidences of renal disease and
hypertension, among other pathologies. Most fructose is cleared by the portal system and …

Background Inadequate copper intake and increased fructose consumption represent two
important nutritional problems in the USA. Dietary copper-fructose interactions alter gut …

Epoxyeicosatrienoic acids (EETs) are metabolites of arachidonic acid via cytochrome P450
(CYP)/epoxygenase and are hydrolyzed by soluble epoxide hydrolase (sEH). Circulating …

Introduction Non-alcoholic fatty liver disease (NAFLD) is characterised by accumulation of
triglycerides and cholesterol within the liver and dysregulation of specific hepatic …

Metabolic syndrome (MetS) is a complex pathological state consisting of metabolic risk
factors such as hypertension, insulin resistance, and obesity. The interconnectivity of cellular …

Neonatal obesity predisposes individuals to obesity throughout life. In rats, neonatal
overfeeding also leads to early accelerated weight gain that persists into adulthood. The …

The purpose of this study was to examine the effects of chronic exercise training and
angiotensin-converting enzyme (ACE) inhibition on peroxisome proliferator-activated …