Regulatory T-cells (Tregs) act at the interface of host and pathogen interactions in human
infectious diseases. Tregs are induced by a wide range of pathogens, but distinct effects of …

Background & Aims Spontaneous resolution of hepatitis C virus (HCV) infection depends
upon a broad T cell response to multiple viral epitopes. However, most patients fail to clear …

Regulatory T (Treg) cells are a specialized subpopulation of CD4+ T cells that enforce
peripheral immune tolerance. Treg cells act to suppress exuberant immune responses, limit …

Cancer is a leading cause of death worldwide. The search for innovative therapeutic
approaches is a principal focus of medical research. Vaccine strategies targeting a number …

The existence of a hyperinflammatory state has been observed in patients with invasive
fungal infections (IFI). It is being postulated whether morbidity from IFI may, in part, be a …

Despite years of research, vaccines against HIV and HCV are not yet available, due largely
to effective viral immunoevasive mechanisms. A novel escape mechanism observed in …

T cells are conventionally categorized into two basic types, viz., CD4+ helper and CD8+
cytotoxic T cells. CD4+ T cells were known to “help” in the activation and differentiation of …

目的探讨慢性丙型肝炎(HCV) 患者CD4+ CD25+ Treg 细胞对外周血树突状细胞的作用.
方法对35 例HCV 患者和35 例健康对照各抽取外周血, 采用密度梯度离心法分离外周血单个核 …

The design of nanocarriers for the delivery of active biomacromolecules requires special
considerations to accomplish both a successful delivery process and the preservation of the …

Background Approximate 180 million people worldwide are infected with hepatitis C virus
(HCV). Historically, vaccination has been the most effective strategy for controlling infections …