GABA is the most common inhibitory neurotransmitter in the vertebrate central nervous
system. Synthesized by glutamic acid decarboxylase, GABA could specifically bind with two …

Allosteric regulation is critical for the functioning of G protein-coupled receptors (GPCRs)
and their signaling pathways. Endogenous allosteric regulators of GPCRs are simple ions …

Rheumatoid arthritis (RA) is a highly disabling chronic autoimmune disease. Multiple factors
contribute to the complex pathological process of RA, in which an abnormal autoimmune …

Numerous studies recently showed that the inhibitory neurotransmitter, γ-aminobutyric acid
(GABA), can stimulate cerebral angiogenesis and promote neurovascular coupling by …

Trigeminal neuralgia (TN) is a unilateral disorder characterized by electric shock-like pain,
abrupt onset and termination, and limited to one or more branches of the trigeminal nerve …

Recent studies have demonstrated the ability of the positive allosteric modulator (PAM) of
the GABA B receptor (GABA B PAM), KK-92A, to suppress operant alcohol self …

GABAB receptors are implicated in numerous central nervous system-based behaviours and
mechanisms, including cognitive processing in preclinical animal models. Homeostatic …

The role of sniffing relative to immune function has attracted considerable attention. The
present study investigated the immunomodulatory effects of peanut oil odor on …

Significance: Microbial neurotransmitters, as potential targets for cancer therapy, are
expected to provide a new perspective on the interaction between the gut microbiome and …

Objective To investigate cellular changes in protein expression in the trigeminal ganglion in
an established preclinical chronic model of temporomandibular joint disorder (TMD) in …