Acute myelogenous leukemia: recent advances in therapy

R Champlin, RP Gale - 1987 - ashpublications.org
Results of treatment of AML have improved over the last decade. With modern remission
induction chemotherapy, most patients achieve complete remission. The median remission …

Effective childhood cancer treatment: the impact of large scale clinical trials in Germany and Austria

C Rossig, H Juergens, M Schrappe… - Pediatric blood & …, 2013 - Wiley Online Library
Abstract In Germany and Austria, more than 90% of pediatric cancer patients are enrolled
into nationwide disease‐specific first‐line clinical trials or interim registries. Essential …

Treatment strategies and long-term results in paediatric patients treated in four consecutive AML-BFM trials

U Creutzig, M Zimmermann, J Ritter, D Reinhardt… - Leukemia, 2005 - nature.com
A total of 1111 children with acute myeloblastic leukaemia (AML) were treated in four
consecutive Berlin–Frankfurt–Münster (BFM) studies from 1978 to 1998. The first …

Principal results of the Medical Research Council's 8th acute myeloid leukaemia trial

JKH Rees, D Swirsky, RG Gray, FGJ Hayhoe - The Lancet, 1986 - Elsevier
Abstract Between 1978 and 1983, 1127 patients with de-novo acute myeloid leukaemia
(AML) were entered into the Medical Research Council (MRC)'s 8th AML trial. All received …

Autologous bone marrow transplantation versus intensive consolidation chemotherapy for acute myeloid leukemia in childhood

Y Ravindranath, AM Yeager, MN Chang… - … England Journal of …, 1996 - Mass Medical Soc
Background The value of autologous bone marrow transplantation in the treatment of
children with acute myeloid leukemia (AML) is unknown. We compared autologous bone …

Identification of two risk groups in childhood acute myelogenous leukemia after therapy intensification in study AML-BFM-83 as compared with study AML-BFM-78 …

U Creutzig, J Ritter, G Schellong - 1990 - ashpublications.org
The main difference between the two cooperative studies on therapy of childhood acute
myelogenous leukemia AML-BFM-78 and AML-BFM-83 was the addition of an 8-day ADE …

Early deaths due to hemorrhage and leukostasis in childhood acute myelogenous leukemia. Associations with hyperleukocytosis and acute monocytic leukemia

U Creutzig, J Ritter, M Budde, A Sutor, G Schellong… - Cancer, 1987 - Wiley Online Library
There were 294 children with acute myelogenous leukemia (AML) entered into the German
AML Berlin, Frankfurt, and Miinster hospitals (BFM) 78 and 83 studies. Thirty (10%) died as a …

Outcome for children with relapsed acute myeloid leukaemia following initial therapy in the Medical Research Council (MRC) AML 10 trial

DKH Webb, K Wheatley, G Harrison, RF Stevens… - Leukemia, 1999 - nature.com
Abstract Between May 1988 and March 1995, 359 children with acute myeloid leukaemia
(AML) were treated in the MRC AML 10 trial. Three risk groups were identified based on …

High-dose cytarabine and daunorubicin as consolidation therapy for acute myeloid leukemia in first remission: long-term follow-up and results.

SN Wolff, RH Herzig, JW Fay, GL Phillips… - Journal of Clinical …, 1989 - ascopubs.org
In an effort to increase the proportion of patients with acute myeloid leukemia (AML)
remaining in continued complete remission (CCR), we administered intensive postremission …

Hyperleukocytosis in childhood acute leukemia: early complications and survival outcomes

S Kittivisuit, N Jongthitinon, P Sripornsawan… - Cancers, 2023 - mdpi.com
Simple Summary Hyperleukocytosis (WBC> 100× 109/L) has been associated with
unfavorable outcomes. Few studies have focused on childhood acute leukemia with …