Personalized medicine tailors therapies, disease prevention, and health maintenance to the
individual, with pharmacogenomics serving as a key tool to improve outcomes and prevent …

Metastatic prostate cancer is a major health burden worldwide, necessitating the continuous
development of effective treatment strategies. Androgen deprivation therapy remains the …

Background The association between clear cell renal cell carcinoma (ccRCC) and
disulfidoptosis remains to be thoroughly investigated. Methods We conducted multiple …

Background RNA methylation is a crucial in many biological functions, and its aberrant
regulation is associated with cancer progression. N6-Methyladenosine (m6A), 5 …

Cutaneous melanoma (CM) is a highly malignant tumor originating from melanocytes, and
its metastasis and recurrence are the major causes of death in CM patients. PANoptosis is a …

Collagen type I α 2 (COL1A2) is a major component of collagen type I. Recently, abnormal
COL1A2 expression has been reported in human cancers. However, the specific role and …

The incidence and mortality rate of gastric cancer (GC) have remained high worldwide.
Although some progress has been made in immunotargeted therapy, the treatment effect …

Background Studies have demonstrated that Sorting nexin 7 (SNX7) functions as an anti-
apoptotic protein in liver tissue and plays a crucial role in the survival of hepatocytes during …

Prostate cancer (PCa) is a critical global public health issue with its incidence on the rise.
Radiation therapy holds a primary role in PCa treatment; however, radiation resistance has …

Olaparib is a pioneering PARP inhibitor (PARPi) approved for treating castration-resistant
prostate cancer (CRPC) tumors harboring DNA repair defects, but clinical resistance has …