Empowering molecule discovery for molecule-caption translation with large language models: A chatgpt perspective
Molecule discovery plays a crucial role in various scientific fields, advancing the design of
tailored materials and drugs, which contributes to the development of society and human …
tailored materials and drugs, which contributes to the development of society and human …
[HTML][HTML] Lessons learnt from COVID-19: computational strategies for facing present and future pandemics
Since its outbreak in December 2019, the COVID-19 pandemic has caused the death of
more than 6.5 million people around the world. The high transmissibility of its causative …
more than 6.5 million people around the world. The high transmissibility of its causative …
[HTML][HTML] Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity
Summary G3BP1/2 are paralogous proteins that promote stress granule formation in
response to cellular stresses, including viral infection. The nucleocapsid (N) protein of …
response to cellular stresses, including viral infection. The nucleocapsid (N) protein of …
[HTML][HTML] Systematic review and meta-analysis of Tuberculosis and COVID-19 Co-infection: Prevalence, fatality, and treatment considerations
Q Wang, Y Cao, X Liu, Y Fu, J Zhang… - PLOS Neglected …, 2024 - journals.plos.org
Background Tuberculosis (TB) and COVID-19 co-infection poses a significant global health
challenge with increased fatality rates and adverse outcomes. However, the existing …
challenge with increased fatality rates and adverse outcomes. However, the existing …
[HTML][HTML] Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication
Abstract G3BP1/2 are paralogous proteins that promote stress granule formation in
response to cellular stresses, including viral infection. G3BP1/2 are prominent interactors of …
response to cellular stresses, including viral infection. G3BP1/2 are prominent interactors of …
[HTML][HTML] In Silico Binding of 2-Aminocyclobutanones to SARS-CoV-2 Nsp13 Helicase and Demonstration of Antiviral Activity
TSH Mohammad, Y Gupta, CT Reidl… - International journal of …, 2023 - mdpi.com
The landscape of viral strains and lineages of SARS-CoV-2 keeps changing and is currently
dominated by Delta and Omicron variants. Members of the latest Omicron variants, including …
dominated by Delta and Omicron variants. Members of the latest Omicron variants, including …
[HTML][HTML] Molecular docking and dynamics simulation study of medicinal fungi derived secondary metabolites as potential inhibitor for COVID-19 treatment
The severity of COVID-19, lack of specific treatment, and controversies on the vaccine's
efficacy demand the development of new drugs against SARS-CoV-2. Fungi produce …
efficacy demand the development of new drugs against SARS-CoV-2. Fungi produce …
[HTML][HTML] Mycolactone: A Broad Spectrum Multitarget Antiviral Active in the Picomolar Range for COVID-19 Prevention and Cure
SO Asiedu, Y Gupta, V Nicolaescu, H Gula… - International journal of …, 2023 - mdpi.com
We have previously shown computationally that Mycolactone (MLN), a toxin produced by
Mycobacterium ulcerans, strongly binds to Munc18b and other proteins, presumably …
Mycobacterium ulcerans, strongly binds to Munc18b and other proteins, presumably …
[HTML][HTML] Network pharmacology and molecular docking: combined computational approaches to explore the antihypertensive potential of Fabaceae species
Hypertension is a major global public health issue, affecting quarter of adults worldwide.
Numerous synthetic drugs are available for treating hypertension; however, they often come …
Numerous synthetic drugs are available for treating hypertension; however, they often come …
[HTML][HTML] Status and Developing Strategies for Neutralizing Monoclonal Antibody Therapy in the Omicron Era of COVID-19
Z Ren, C Shen, J Peng - Viruses, 2023 - mdpi.com
The monoclonal antibody (mAb)-based treatment is a highly valued therapy against COVID-
19, especially for individuals who may not have strong immune responses to the vaccine …
19, especially for individuals who may not have strong immune responses to the vaccine …