Prenatal environmental exposures, epigenetics, and disease

F Perera, J Herbstman - Reproductive toxicology, 2011 - Elsevier
This review summarizes recent evidence that prenatal exposure to diverse environmental
chemicals dysregulates the fetal epigenome, with potential consequences for subsequent …

Interactions between polycyclic aromatic hydrocarbons in complex mixtures and implications for cancer risk assessment

IWH Jarvis, K Dreij, Å Mattsson, B Jernström, U Stenius - Toxicology, 2014 - Elsevier
In this review we discuss the effects of exposure to complex PAH mixtures in vitro and in vivo
on mechanisms related to carcinogenesis. Of particular concern regarding exposure to …

Polycyclic aromatic hydrocarbons as skin carcinogens: comparison of benzo [a] pyrene, dibenzo [def, p] chrysene and three environmental mixtures in the FVB/N …

LK Siddens, A Larkin, SK Krueger, CA Bradfield… - Toxicology and applied …, 2012 - Elsevier
The polycyclic aromatic hydrocarbon (PAH), benzo [a] pyrene (BaP), was compared to
dibenzo [def, p] chrysene (DBC) and combinations of three environmental PAH mixtures …

[HTML][HTML] The aryl hydrocarbon receptor meets immunology: friend or foe? A little of both

W Julliard, JH Fechner, JD Mezrich - Frontiers in immunology, 2014 - frontiersin.org
The aryl hydrocarbon receptor (AHR) has long been studied by toxicologists as a ligand-
activated transcription factor that is activated by dioxin and other environmental pollutants …

[HTML][HTML] Benzo [a] pyrene (BaP) metabolites predominant in human plasma following escalating oral micro-dosing with [14C]-BaP

MLV Maier, LK Siddens, JM Pennington… - Environment …, 2022 - Elsevier
Abstract Benzo [a] pyrene (BaP) is formed by incomplete combustion of organic materials
(petroleum, coal, tobacco, etc.). BaP is designated by the International Agency for Research …

[HTML][HTML] Polycyclic aromatic hydrocarbons

H Choi, R Harrison, H Komulainen… - WHO guidelines for …, 2010 - ncbi.nlm.nih.gov
The term polycyclic organic matter (POM) defines a broad class of compounds that generally
includes all organic structures containing three or more fused aromatic rings. These …

Structure− function relationships of inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2C9, and 3A4 by 33 flavonoid derivatives

T Shimada, K Tanaka, S Takenaka… - Chemical research in …, 2010 - ACS Publications
Structure− function relationships for the inhibition of human cytochrome P450s (P450s) 1A1,
1A2, 1B1, 2C9, and 3A4 by 33 flavonoid derivatives were studied. Thirty-two of the 33 …

Combined effects of nanoparticles and other environmental contaminants on human health-an issue often overlooked

V Forest - NanoImpact, 2021 - Elsevier
Air pollution is considered as a major public health issue worldwide. It consists of a complex
mixture of pollutants including nanoparticles to which we are increasingly exposed to due to …

Polycyclic aromatic hydrocarbons in binary mixtures modulate the efficiency of benzo [a] pyrene to form DNA adducts in human cells

A Tarantini, A Maître, E Lefèbvre, M Marques, A Rajhi… - Toxicology, 2011 - Elsevier
Exposure to polycyclic aromatic hydrocarbons (PAHs) always involves complex mixtures
that may induce synergistic or antagonistic effects on the genotoxic properties and make risk …

The history, genotoxicity, and carcinogenicity of carbon-based fuels and their emissions. Part 3: Diesel and gasoline

LD Claxton - Mutation research/reviews in mutation research, 2015 - Elsevier
Within this review the genotoxicity of diesel and gasoline fuels and emissions is placed in an
historical context. New technologies have changed the composition of transportation …