Prenatal environmental exposures, epigenetics, and disease
F Perera, J Herbstman - Reproductive toxicology, 2011 - Elsevier
This review summarizes recent evidence that prenatal exposure to diverse environmental
chemicals dysregulates the fetal epigenome, with potential consequences for subsequent …
chemicals dysregulates the fetal epigenome, with potential consequences for subsequent …
Interactions between polycyclic aromatic hydrocarbons in complex mixtures and implications for cancer risk assessment
In this review we discuss the effects of exposure to complex PAH mixtures in vitro and in vivo
on mechanisms related to carcinogenesis. Of particular concern regarding exposure to …
on mechanisms related to carcinogenesis. Of particular concern regarding exposure to …
Polycyclic aromatic hydrocarbons as skin carcinogens: comparison of benzo [a] pyrene, dibenzo [def, p] chrysene and three environmental mixtures in the FVB/N …
LK Siddens, A Larkin, SK Krueger, CA Bradfield… - Toxicology and applied …, 2012 - Elsevier
The polycyclic aromatic hydrocarbon (PAH), benzo [a] pyrene (BaP), was compared to
dibenzo [def, p] chrysene (DBC) and combinations of three environmental PAH mixtures …
dibenzo [def, p] chrysene (DBC) and combinations of three environmental PAH mixtures …
[HTML][HTML] The aryl hydrocarbon receptor meets immunology: friend or foe? A little of both
W Julliard, JH Fechner, JD Mezrich - Frontiers in immunology, 2014 - frontiersin.org
The aryl hydrocarbon receptor (AHR) has long been studied by toxicologists as a ligand-
activated transcription factor that is activated by dioxin and other environmental pollutants …
activated transcription factor that is activated by dioxin and other environmental pollutants …
[HTML][HTML] Benzo [a] pyrene (BaP) metabolites predominant in human plasma following escalating oral micro-dosing with [14C]-BaP
MLV Maier, LK Siddens, JM Pennington… - Environment …, 2022 - Elsevier
Abstract Benzo [a] pyrene (BaP) is formed by incomplete combustion of organic materials
(petroleum, coal, tobacco, etc.). BaP is designated by the International Agency for Research …
(petroleum, coal, tobacco, etc.). BaP is designated by the International Agency for Research …
[HTML][HTML] Polycyclic aromatic hydrocarbons
H Choi, R Harrison, H Komulainen… - WHO guidelines for …, 2010 - ncbi.nlm.nih.gov
The term polycyclic organic matter (POM) defines a broad class of compounds that generally
includes all organic structures containing three or more fused aromatic rings. These …
includes all organic structures containing three or more fused aromatic rings. These …
Structure− function relationships of inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2C9, and 3A4 by 33 flavonoid derivatives
T Shimada, K Tanaka, S Takenaka… - Chemical research in …, 2010 - ACS Publications
Structure− function relationships for the inhibition of human cytochrome P450s (P450s) 1A1,
1A2, 1B1, 2C9, and 3A4 by 33 flavonoid derivatives were studied. Thirty-two of the 33 …
1A2, 1B1, 2C9, and 3A4 by 33 flavonoid derivatives were studied. Thirty-two of the 33 …
Combined effects of nanoparticles and other environmental contaminants on human health-an issue often overlooked
V Forest - NanoImpact, 2021 - Elsevier
Air pollution is considered as a major public health issue worldwide. It consists of a complex
mixture of pollutants including nanoparticles to which we are increasingly exposed to due to …
mixture of pollutants including nanoparticles to which we are increasingly exposed to due to …
Polycyclic aromatic hydrocarbons in binary mixtures modulate the efficiency of benzo [a] pyrene to form DNA adducts in human cells
A Tarantini, A Maître, E Lefèbvre, M Marques, A Rajhi… - Toxicology, 2011 - Elsevier
Exposure to polycyclic aromatic hydrocarbons (PAHs) always involves complex mixtures
that may induce synergistic or antagonistic effects on the genotoxic properties and make risk …
that may induce synergistic or antagonistic effects on the genotoxic properties and make risk …
The history, genotoxicity, and carcinogenicity of carbon-based fuels and their emissions. Part 3: Diesel and gasoline
LD Claxton - Mutation research/reviews in mutation research, 2015 - Elsevier
Within this review the genotoxicity of diesel and gasoline fuels and emissions is placed in an
historical context. New technologies have changed the composition of transportation …
historical context. New technologies have changed the composition of transportation …