Although there has been some progress in the efficacy of anti-cancer drugs, drug resistance
remains challenging. Cancer stem cells (CSCs) are self-renewing and differentiate into …

Cisplatin is a well-known platinum-based chemotherapy medication that is widely utilized for
some malignancies. Despite the direct cytotoxic consequences of cisplatin on tumor cells …

Cisplatin resistance poses a substantial hurdle in effectively treating head and neck
squamous cell carcinoma (HNSCC). Utilizing multiple tumor models and examining an …

Purpose Resistance to chemotherapy and radiotherapy is the primary cause of a poor
prognosis in oncological patients. Researchers identified many possible mechanisms …

Introduction Cisplatin is a very effective chemotherapeutic agent against a variety of solid
tumors. Unfortunately, cisplatin causes permanent sensorineural hearing loss in at least two …

Head and neck squamous cell carcinoma (HNSCC) is the most common malignant tumor of
the head and neck, and the prognosis of patients is poor due to chemotherapeutic …

Head and neck cancer (HNC) therapy is limited; therefore, new solutions are increasingly
being sought among flavonoids, which exhibit numerous biological properties, including …

Purpose: To identify molecular subtypes of oxidative stress-related genes in head and neck
squamous cell carcinoma (HNSCC) and to construct a scoring model of oxidative stress …

This study aims to investigate the role of partial epithelial to mesenchymal transition (pEMT)-
related proteins in modulating Cisplatin resistance in head and neck squamous cell …

Simple Summary Head and neck cancers (HNSCCs), especially in the advanced stages, are
predominantly treated by radiochemotherapy, including cisplatin. The cure rates are clearly …