The microbial landscape of colorectal cancer
MT White, CL Sears - Nature Reviews Microbiology, 2024 - nature.com
Colorectal cancer (CRC) is a substantial source of global morbidity and mortality in dire
need of improved prevention and treatment strategies. As our understanding of CRC grows …
need of improved prevention and treatment strategies. As our understanding of CRC grows …
[HTML][HTML] Current understanding of the intratumoral microbiome in various tumors
C Xue, Q Chu, Q Zheng, X Yuan, Y Su, Z Bao, J Lu… - Cell Reports …, 2023 - cell.com
It is estimated that in the future, the number of new cancer cases worldwide will exceed the
19.3 million recorded in 2020, and the number of deaths will exceed 10 million. Cancer …
19.3 million recorded in 2020, and the number of deaths will exceed 10 million. Cancer …
Emerging roles of intratumor microbiota in cancer metastasis
A Fu, B Yao, T Dong, S Cai - Trends in Cell Biology, 2023 - cell.com
Cancer metastasis is the leading cause of mortality in patients with cancer. Theories have
been developed to explain the causes and principles of metastasis. Metastasis is attributed …
been developed to explain the causes and principles of metastasis. Metastasis is attributed …
[HTML][HTML] Gut microbiota in colorectal cancer: biological role and therapeutic opportunities
Simple Summary Colorectal cancer (CRC) is the second-leading cause of cancer-related
deaths worldwide. In this review article, we examine the role of gut microbiota in the …
deaths worldwide. In this review article, we examine the role of gut microbiota in the …
[HTML][HTML] Intracellular bacteria in cancer—Prospects and debates
Recent evidence suggests that some human cancers may harbor low-biomass microbial
ecosystems, spanning bacteria, viruses, and fungi. Bacteria, the most-studied kingdom in …
ecosystems, spanning bacteria, viruses, and fungi. Bacteria, the most-studied kingdom in …
[HTML][HTML] Intratumoural microbiota: a new frontier in cancer development and therapy
Y Cao, H Xia, X Tan, C Shi, Y Ma, D Meng… - … and Targeted Therapy, 2024 - nature.com
Human microorganisms, including bacteria, fungi, and viruses, play key roles in several
physiological and pathological processes. Some studies discovered that tumour tissues …
physiological and pathological processes. Some studies discovered that tumour tissues …
Synergistic Target of Intratumoral Microbiome and Tumor by Metronidazole–Fluorouridine Nanoparticles
C Gao, X Wang, B Yang, W Yuan, W Huang, G Wu… - ACS …, 2023 - ACS Publications
Clinical and experimental evidence confirmed bacterial infiltration in a variety of tumors,
which is related to the progression and therapeutic effects of the tumors. Although the …
which is related to the progression and therapeutic effects of the tumors. Although the …
Emerging strategies for combating Fusobacterium nucleatum in colorectal cancer treatment: Systematic review, improvements and future challenges
H Liu, Y Yu, A Dong, M Elsabahy, YW Yang… - Exploration, 2024 - Wiley Online Library
Colorectal cancer (CRC) is generally characterized by a high prevalence of Fusobacterium
nucleatum (F. nucleatum), a spindle‐shaped, Gram‐negative anaerobe pathogen derived …
nucleatum (F. nucleatum), a spindle‐shaped, Gram‐negative anaerobe pathogen derived …
[HTML][HTML] Fusobacterium nucleatum outer membrane vesicles activate autophagy to promote oral cancer metastasis
G Chen, C Gao, S Jiang, Q Cai, R Li, Q Sun… - Journal of Advanced …, 2024 - Elsevier
Introduction Metastasis is an important cause of high mortality and lethality of oral cancer.
Fusobacterium nucleatum (Fn) can promote tumour metastasis. Outer membrane vesicles …
Fusobacterium nucleatum (Fn) can promote tumour metastasis. Outer membrane vesicles …
[HTML][HTML] Microbial composition of tumorous and adjacent gastric tissue is associated with prognosis of gastric cancer
K Lehr, D Nikitina, R Vilchez-Vargas… - Scientific Reports, 2023 - nature.com
Helicobacter pylori (H. pylori) infection has been considered as the main causal factor in
gastric carcinogenesis, but other bacterial species may also play an important role in …
gastric carcinogenesis, but other bacterial species may also play an important role in …