Blood coagulation can be initiated by two pathways: the extrinsic pathway, which is triggered
by release of tissue factor from the site of injury, and the intrinsic system, which is stimulated …

Despite efforts to elucidate the pathogenesis of dengue fever, the progression into severe
disease remains poorly understood. In-vitro findings suggest that coagulopathy and …

Background—Bivalirudin, a direct thrombin inhibitor, is a widely used adjunctive therapy in
patients undergoing percutaneous intervention (PCI). Thrombin is a highly potent agonist of …

The presence of activation peptides (AP) of the vitamin K-dependent proteins in the
phlebotomy blood of human subjects suggests that active serine proteases may circulate in …

As a tribute to Butantan Institute in its 120th anniversary, this review describes some of the
scientific research efforts carried out in the study of Lonomia envenoming in Brazil, a country …

The formation of a thrombus in an epicardial artery may result in an acute myocardial
infarction (AMI). Despite major advances in acute treatment using network approaches to …

Previous studies have highlighted that bubble-induced platelet aggregation is a predictor
index of decompression sickness (DCS) severity in animals and bubble formation after a …

Homocysteine, derived from the demethylation of the ammo acid methionine, is either further
catabolised by trans-sulfuration to cysteine or remethylated to methionine. Remethylation to …

BACKGROUND: Because acute coronary syndromes (ACS) are caused by intracoronary
thrombosis, plasma markers of coagulation have relevance for early diagnosis. AIMS AND …

Aims This nationwide study aimed to determine whether venous thromboembolism (VTE)
shares familial susceptibility with coronary heart disease (CHD). Methods and results Data …