The 5-10-methylenetetrahydrofolate reductase (MTHFR) enzyme is vital for cellular
homeostasis due to its key functions in the one-carbon cycle, which include methionine and …

Vitamin B12, also known as the anti-pernicious anemia factor, is an essential micronutrient
totally dependent on dietary sources that is commonly integrated with food supplements …

Vitamin B12 is an essential nutrient that is not made by plants; consequently, unfortified
plant-based foods are not a reliable supply. Recent estimates suggest high rates of vitamin …

Silymarin has been used for improving hepatic damage and lipid disorders, but its action
mechanism remains to be clarified. Here, we investigate the contributions of the gut …

Owing to its capacity to damage the endocrine system, bisphenol A (BPA) is being
substituted in common consumer products by chemically related compounds, including …

Vitamin B12 plays a key role in DNA stability. Research indicates that vitamin B12 deficiency
leads to indirect DNA damage, and vitamin B12 supplementation may reverse this effect …

Metabolism and nutrition have a significant role in epigenetic modifications such as DNA
methylation, which can influence gene expression. Recently, it has been suggested that …

Childhood obesity represents a serious public health burden. Despite excessive dietary
consumption, children with obesity present high rates of micronutrient deficiencies, such as …

The prevalence of non-alcoholic fatty liver disease (NAFLD) is increasing and approximately
25% of the global population may have NAFLD. NAFLD is associated with obesity and …

Objective To systematically review the evidence for whether habitual or different levels of
experimental intake of vitamin B12 from diet and supplements is sufficient to ensure …