[HTML][HTML] Exploring the promising potential of induced pluripotent stem cells in cancer research and therapy

M Chehelgerdi, F Behdarvand Dehkordi… - Molecular Cancer, 2023 - Springer
The advent of iPSCs has brought about a significant transformation in stem cell research,
opening up promising avenues for advancing cancer treatment. The formation of cancer is a …

[HTML][HTML] Preclinical Models of Neuroblastoma—Current Status and Perspectives

E Krawczyk, J Kitlińska - Cancers, 2023 - mdpi.com
Simple Summary Neuroblastoma is a pediatric tumor originating from the precursors of
sympathetic nerves. The disease is known for its high heterogeneity. Hence, developing …

[HTML][HTML] Modeling human brain rhabdoid tumor by inactivating tumor suppressor genes in induced pluripotent stem cells

T Hua, Y Xue, DB Sarker, S Kiran, Y Li, QXA Sang - Bioactive Materials, 2024 - Elsevier
Atypical teratoid/rhabdoid tumor (ATRT) is a rare childhood malignancy that originates in the
central nervous system. Over ninety-five percent of ATRT patients have biallelic inactivation …

[HTML][HTML] Stem cell modeling of nervous system tumors

FB Furnari, C Anastasaki, S Bian… - Disease Models & …, 2024 - journals.biologists.com
Nervous system tumors, particularly brain tumors, represent the most common tumors in
children and one of the most lethal tumors in adults. Despite decades of research, there are …