Objective Immunoregulation is a complex and critical process in the pathological process of
spinal cord injury (SCI), which is regulated by various factors and plays an important role in …

Neurodegenerative diseases (NDDs) are a collection of incapacitating disorders in which
neuroinflammation and neuronal apoptosis are major pathological consequences due to …

Argatroban is a synthetic thrombin inhibitor approved by US Food and Drug Administration
for the treatment of thrombosis. However, whether it plays a role in the repair of spinal cord …

Spinal cord injury (SCI) is one of the most serious health problems, with no effective therapy.
Recent studies indicate that Fisetin, a natural polyphenolic flavonoid, exhibits multiple …

Spinal cord injury is a serious traumatic nervous system disorder characterized by extensive
neuronal apoptosis. Oxidative stress, a key factor in neuronal apoptosis, leads to the …

Spinal cord injury (SCI) is a traumatic condition of the central nervous system that causes
paralysis of the limbs. Micro electric fields (EF) have been implicated in a novel therapeutic …

The secondary injury is more serious after traumatic brain injury (TBI) compared with primary
injury. Release of excessive reactive oxygen species (ROS) and Ca2+ influx at the damaged …

The adverse microenvironment, including neuroinflammation, hinders the recovery of spinal
cord injury (SCI). Regulating microglial polarization to alleviate neuroinflammation at the …

Cadmium (Cd), a heavy metal, is used in a wide range of applications, such as plastics,
electroplating process, electronics, and so forth. Due to its bioaccumulation ability, Cd can …

Abstract Background Spinal cord injuries (SCIs) trigger a cascade of detrimental processes,
encompassing neuroinflammation and oxidative stress (OS), ultimately leading to neuronal …