Oxidized low-density lipoprotein and atherosclerosis implications in antioxidant therapy

S Mitra, A Deshmukh, R Sachdeva, J Lu… - The American journal of …, 2011 - Elsevier
Abstract Low-density lipoprotein (LDL)-cholesterol is important for cellular function, but in
high concentrations, it can lead to atheroma formation. Over the past several decades, it has …

Oxidative stress and lectin-like ox-LDL-receptor LOX-1 in atherogenesis and tumorigenesis

J Lu, S Mitra, X Wang, M Khaidakov… - Antioxidants & redox …, 2011 - liebertpub.com
Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) has been identified as a
major receptor for oxidized low-density lipoprotein (ox-LDL) in endothelial cells, monocytes …

Modified low density lipoprotein and lipoprotein-containing circulating immune complexes as diagnostic and prognostic biomarkers of atherosclerosis and type 1 …

AN Orekhov, YV Bobryshev, IA Sobenin… - International journal of …, 2014 - mdpi.com
In atherosclerosis; blood low-density lipoproteins (LDL) are subjected to multiple enzymatic
and non-enzymatic modifications that increase their atherogenicity and induce …

Relationship of autoantibodies to MDA-LDL and ApoB-immune complexes to sex, ethnicity, subclinical atherosclerosis, and cardiovascular events

A Prasad, P Clopton, C Ayers, A Khera… - … , and vascular biology, 2017 - Am Heart Assoc
Objective—Modifications of lipid constituents within atherosclerotic lesions generate
neoepitopes that activate innate and adaptive immune responses. We aimed to define the …

Probiotic soy product supplemented with isoflavones improves the lipid profile of moderately hypercholesterolemic men: a randomized controlled trial

D Cardoso Umbelino Cavallini… - Nutrients, 2016 - mdpi.com
Background: Cardiovascular disease is the leading cause of worldwide morbidity and
mortality. Several studies have demonstrated that specific probiotics affect the host's …

Oxidized low-density lipoproteins upregulate proline oxidase to initiate ROS-dependent autophagy

O Zabirnyk, W Liu, S Khalil, A Sharma… - …, 2010 - academic.oup.com
Epidemiological studies showed that high levels of oxidized low-density lipoproteins
(oxLDLs) are associated with increased cancer risk. We examined the direct effect of …

Antioxidant effects of statins in the management of cardiometabolic disorders

S Lim, P Barter - Journal of atherosclerosis and thrombosis, 2014 - jstage.jst.go.jp
Address for correspondence: Soo Lim, Internal Medicine, Seoul National University College
of Medicine and Seoul National University Bundang Hospital, 300 Gumi-dong, Bundang-gu …

[HTML][HTML] Low-density lipoprotein oxidation biomarkers in human health and disease and effects of bioactive compounds

BM Winklhofer-Roob, G Faustmann, JM Roob - Free Radical Biology and …, 2017 - Elsevier
Based on the significance of oxidized low-density lipoprotein (LDL) in health and disease,
this review focuses on human studies addressing oxidation of LDL, including three lines of …

Effects of isoflavone-supplemented soy yogurt on lipid parameters and atherosclerosis development in hypercholesterolemic rabbits: a randomized double-blind study

DCU Cavallini, DSP Abdalla, RC Vendramini… - Lipids in Health and …, 2009 - Springer
Background There is increasing interest in natural treatments to control dyslipidemia and
reduce the risk of cardiovascular disease. Previous studies have demonstrated the …

Auto-antibodies as emergent prognostic markers and possible mediators of ischemic cardiovascular diseases

P Roux-Lombard, S Pagano, F Montecucco… - Clinical reviews in …, 2013 - Springer
During the last 15 years, a growing body of evidence supported the fact that auto-antibodies
represent not only emergent markers but also active mediators of cardiovascular disease …