[HTML][HTML] HDLBP-stabilized lncFAL inhibits ferroptosis vulnerability by diminishing Trim69-dependent FSP1 degradation in hepatocellular carcinoma

J Yuan, T Lv, J Yang, Z Wu, L Yan, J Yang, Y Shi - Redox Biology, 2022 - Elsevier
Recent studies have suggested that exploring the potential mechanisms regulating
ferroptosis vulnerability may contribute to improving the systemic therapeutic efficacy in …

Advances in the molecular mechanism and targeted therapy of radioactive-iodine refractory differentiated thyroid cancer

L Zhang, Z Li, M Zhang, H Zou, Y Bai, Y Liu, J Lv, L Lv… - Medical Oncology, 2023 - Springer
Most patients with differentiated thyroid cancer have a good prognosis after radioactive
iodine-131 treatment, but there are still a small number of patients who are not sensitive to …

[HTML][HTML] Lenvatinib resistance mechanism and potential ways to conquer

W Bo, Y Chen - Frontiers in Pharmacology, 2023 - frontiersin.org
Lenvatinib (LVN) has been appoved to treat advanced renal cell carcinoma, differentiated
thyroid carcinoma, hepatocellular carcinoma. Further other cancer types also have been …

[HTML][HTML] Lutein induces reactive oxygen species-mediated apoptosis in gastric cancer AGS cells via NADPH oxidase activation

JW Eom, JW Lim, H Kim - Molecules, 2023 - mdpi.com
Disruption of apoptosis leads to cancer cell progression; thus, anticancer agents target
apoptosis of cancer cells. Reactive oxygen species (ROS) induce apoptosis by activating …

[HTML][HTML] Oxidative stress correlates with more aggressive features in thyroid cancer

M Muzza, G Pogliaghi, C Colombo, E Carbone… - Cancers, 2022 - mdpi.com
Simple Summary Several pieces of evidence indicate an impact of oxidative stress (OS) in
the pathogenesis and progression of thyroid cancer. The aim of the study was to investigate …

NADPH oxidase 4 deficiency attenuates experimental osteoarthritis in mice

F Renaudin, K Oudina, M Gerbaix, MMG Subilia… - RMD open, 2023 - rmdopen.bmj.com
Objective Low-grade inflammation plays a pivotal role in osteoarthritis (OA) through
exposure to reactive oxygen species (ROS). In chondrocytes, NADPH oxidase 4 (NOX4) is …

Copper-based metal–organic framework co-loaded doxorubicin and curcumin for anti-cancer with synergistic apoptosis and ferroptosis therapy

D Guo, Q Lin, N Liu, Q Jin, C Liu, Y Wang, X Zhu… - International Journal of …, 2024 - Elsevier
The combination of chemotherapy and ferroptosis therapy can greatly improve the efficiency
of tumor treatment. However, ferroptosis-based therapy is limited by the unsatisfactory …

Involvement of spinal NADPH oxidase 4 and endoplasmic reticulum stress in morphine‐tolerant rats

X Xiao, J Yang, Q Bai, Z Wang, Y Chen… - Journal of …, 2023 - Wiley Online Library
Morphine tolerance (MT) is currently a challenging issue related to intractable pain
treatment. Studies have shown that reactive oxygen species (ROSs) derived from NADPH …

[HTML][HTML] The role and mechanism of NADPH oxidase in the development and progression of thyroid carcinoma

H Dang, J Sheng, P Tang, X Peng… - American Journal of …, 2023 - ncbi.nlm.nih.gov
Thyroid cancer is the fastest increasing cancer in both men and women and is the most
common endocrine cancer. Researchers have gradually intensified their research on the …

[HTML][HTML] 慢性饥饿应激通过增强ITGB1 表达促进结直肠癌细胞迁移

李思雨, 曹静桦, 王凤伟 - 肿瘤防治研究, 2024 - zlfzyj.com
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