Regulation of apoptotic pathways during endometriosis: from the molecular basis to the future perspectives
V Vetvicka, AS Laganà, FM Salmeri, O Triolo… - Archives of gynecology …, 2016 - Springer
Purpose Endometriosis is defined as the presence of endometrial-like endometrial cells,
glands and stroma outside the uterus, causing a strong inflammatory-like microenvironment …
glands and stroma outside the uterus, causing a strong inflammatory-like microenvironment …
The Known, the Unknown and the Future of the Pathophysiology of Endometriosis
MA Ochoa Bernal, AT Fazleabas - International Journal of Molecular …, 2024 - mdpi.com
Endometriosis is one of the most common causes of chronic pelvic pain and infertility,
affecting 10% of women of reproductive age. A delay of up to 9 years is estimated between …
affecting 10% of women of reproductive age. A delay of up to 9 years is estimated between …
Activated hippo/yes-associated protein pathway promotes cell proliferation and anti-apoptosis in endometrial stromal cells of endometriosis
Y Song, J Fu, M Zhou, L Xiao, X Feng… - The Journal of …, 2016 - academic.oup.com
Context: The imbalance in cell proliferation and apoptosis is considered an important role in
the pathogenesis of endometriosis, but the exact mechanisms remains unclear. A newly …
the pathogenesis of endometriosis, but the exact mechanisms remains unclear. A newly …
[HTML][HTML] Peptide ligands targeting FGF receptors promote recovery from dorsal root crush injury via AKT/mTOR signaling
Y Zhao, Q Wang, C Xie, Y Cai, X Chen, Y Hou, L He… - Theranostics, 2021 - ncbi.nlm.nih.gov
Background: Fibroblast growth factor receptors (FGFRs) are key targets for nerve
regeneration and repair. The therapeutic effect of exogenous recombinant FGFs in vivo is …
regeneration and repair. The therapeutic effect of exogenous recombinant FGFs in vivo is …
Cell-penetrating peptide and siRNA-mediated therapeutic effects on endometriosis and cancer in vitro models
Gene therapy is a powerful tool for the development of new treatment strategies for various
conditions, by aiming to transport biologically active nucleic acids into diseased cells. To …
conditions, by aiming to transport biologically active nucleic acids into diseased cells. To …
Homing peptide-based targeting of tenascin-C and fibronectin in endometriosis
The current diagnostic and therapeutic strategies for endometriosis are limited. Although
endometriosis is a benign condition, some of its traits, such as increased cell invasion …
endometriosis is a benign condition, some of its traits, such as increased cell invasion …
Oxidation-sensitive nociception involved in endometriosis-associated pain
K Ray, J Fahrmann, B Mitchell, D Paul, H King, C Crain… - Pain, 2015 - journals.lww.com
Endometriosis is a disease characterized by the growth of endometrial tissue outside the
uterus and is associated with chronic pelvic pain. Peritoneal fluid (PF) of women with …
uterus and is associated with chronic pelvic pain. Peritoneal fluid (PF) of women with …
[HTML][HTML] Frankincense ameliorates endometriosis via inducing apoptosis and reducing adhesion
Background Frankincense, a resin derived from trees of the Boswellia genus, has been used
as an incense and a type of herbal medicine for treating inflammatory diseases such …
as an incense and a type of herbal medicine for treating inflammatory diseases such …
Establishment of an immortalized endometriotic stromal cell line from human ovarian endometrioma
Endometrial-like stromal cells, one of the main components of endometriotic lesions, are an
important in vitro model for studying cellular and molecular mechanisms associated with …
important in vitro model for studying cellular and molecular mechanisms associated with …
Targeted modification of the cationic anticancer peptide HPRP-A1 with iRGD to improve specificity, penetration, and tumor-tissue accumulation
C Hu, Y Huang, Y Chen - Molecular Pharmaceutics, 2018 - ACS Publications
The chimeric peptide HPRP-A1-iRGD, composed of a chemically conjugated tumor-
homing/penetration domain (iRGD) and a cationic anticancer peptide domain (HPRP-A1) …
homing/penetration domain (iRGD) and a cationic anticancer peptide domain (HPRP-A1) …