Mitochondria play key roles in bioenergetics, metabolism, and signaling; therefore, stable
mitochondrial function is essential for cell survival, particularly in energy-intensive neuronal …

Endocannabinoids (eCBs) are amongst the most ubiquitous signaling molecules in the
nervous system. Over the past few decades, observations based on a large volume of work …

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a disease now well-
documented as having arisen commonly from a viral infection, but also from other external …

Precise regulation of cellular metabolism is hypothesized to constitute a vital component of
the developmental sequence underlying the life-long generation of hippocampal neurons …

Background: Depression is the most debilitating neuropsychiatric disorder with significant
impact on socio-occupational and well being of individual. The exact pathophysiology of …

Schizophrenia is a neurodevelopmental disorder whose clinical features include
impairments in perception, cognition and motivation. These impairments reflect alterations in …

Background Ischemic stroke can induce changes in mitochondrial morphology and function.
As a regulatory gene in mitochondria, optic atrophy 1 (OPA1) plays a pivotal role in the …

Mitochondria play a critical role in regulating cellular functions including bioenergetics,
calcium homeostasis, redox signalling, and apoptotic cell death. Mitochondria are also …

The formation, maintenance and reorganization of synapses are critical for brain
development and the responses of neuronal circuits to environmental challenges. Here we …

Dominance hierarchies are integral aspects of social groups, yet whether personality traits
may predispose individuals to a particular rank remains unclear. Here we show that trait …