Protein cages: from fundamentals to advanced applications

TGW Edwardson, MD Levasseur, S Tetter… - Chemical …, 2022 - ACS Publications
Proteins that self-assemble into polyhedral shell-like structures are useful molecular
containers both in nature and in the laboratory. Here we review efforts to repurpose diverse …

Baculovirus: an insect-derived vector for diverse gene transfer applications

KJ Airenne, YC Hu, TA Kost, RH Smith, RM Kotin… - Molecular Therapy, 2013 - cell.com
Insect-derived baculoviruses have emerged as versatile and safe workhorses of
biotechnology. Baculovirus expression vectors (BEVs) have been applied widely for crop …

Spatial control of in vivo CRISPR–Cas9 genome editing via nanomagnets

H Zhu, L Zhang, S Tong, CM Lee… - Nature biomedical …, 2019 - nature.com
The potential of clustered regularly interspaced short palindromic repeats (CRISPR)–
CRISPR associated protein 9 (Cas9)-based therapeutic genome editing is hampered by …

The recent advances of magnetic nanoparticles in medicine

T Guo, M Lin, J Huang, C Zhou, W Tian… - Journal of …, 2018 - Wiley Online Library
With the progress of nanotechnology and molecular biology, nanoparticles have been
widely studied and applied in biomedicine. Particularly, characterized by unique magnetic …

Impacts of nano-metal oxides on hydrogen production in anaerobic digestion of palm oil mill effluent–A novel approach

P Mishra, S Thakur, DM Mahapatra, Z Ab Wahid… - international journal of …, 2018 - Elsevier
In the present study, hydrogen production from palm oil mill effluent (POME) was
investigated with the incorporation of nanoparticles (NPs) comprising of nickel (NiO) and …

MicroRNA delivery for regenerative medicine

B Peng, Y Chen, KW Leong - Advanced drug delivery reviews, 2015 - Elsevier
MicroRNA (miRNA) directs post-transcriptional regulation of a network of genes by targeting
mRNA. Although relatively recent in development, many miRNAs direct differentiation of …

CRISPR technologies for stem cell engineering and regenerative medicine

MN Hsu, YH Chang, VA Truong, PL Lai… - Biotechnology …, 2019 - Elsevier
CRISPR/Cas9 system exploits the concerted action of Cas9 nuclease and programmable
single guide RNA (sgRNA), and has been widely used for genome editing. The Cas9 …

Osteogenic differentiation of adipose-derived stem cells and calvarial defect repair using baculovirus-mediated co-expression of BMP-2 and miR-148b

YH Liao, YH Chang, LY Sung, KC Li, CL Yeh, TC Yen… - Biomaterials, 2014 - Elsevier
Repair of large calvarial bony defect remains a challenge for orthopedic surgeons. Since
microRNAs (miRNAs) modulate the osteogenesis of osteoprogenitor cells, we aimed to …

Baculoviruses: sophisticated pathogens of insects

RJ Clem, AL Passarelli - PLoS pathogens, 2013 - journals.plos.org
The baculoviruses (family: Baculoviridae) are a group of large DNA viruses that infect
insects. These viruses are well known for their utility and versatility as gene expression …

The magic staff: a comprehensive overview of baculovirus-based technologies applied to human and animal health

ML Pidre, PN Arrías, LC Amorós Morales… - Viruses, 2022 - mdpi.com
Baculoviruses are enveloped, insect-specific viruses with large double-stranded DNA
genomes. Among all the baculovirus species, Autographa californica multiple …