There is now overwhelming experimental and clinical evidence that atherosclerosis is a
chronic inflammatory disease. Lessons from genome-wide association studies, advanced in …

The diverse leukocyte infiltrate in atherosclerotic mouse aortas was recently analyzed in 9
single-cell RNA sequencing and 2 mass cytometry studies. In a comprehensive meta …

The cardiovascular system is subject to hyperlipidaemic, inflammatory, and pro-oxidant
stressors. Over time, these factors drive prevalent chronic diseases, of which atherosclerosis …

Cardiovascular disease (CVD) is the number one cause of death in the United States and
worldwide. The most common cause of cardiovascular disease is atherosclerosis, or …

The endoplasmic reticulum (ER) is an important organelle that regulates several
fundamental cellular processes, and ER dysfunction has implications for many intracellular …

Immune mechanisms are critically involved in the pathogenesis of atherosclerosis and its
clinical manifestations. Associations of specific antibody levels and defined B-cell subsets …

Because atherosclerotic cardiovascular disease is a leading cause of death worldwide,
understanding inflammatory processes underpinning its pathology is critical. B cells have …

Atherosclerotic cardiovascular disease is a major cause of disability and death worldwide.
Most therapeutic approaches target traditional risk factors but ignore the fundamental role of …

Allergic diseases are allergen‐induced immunological disorders characterized by the
development of type 2 immunity and IgE responses. The prevalence of allergic diseases has …

Atherosclerosis is a lipid-driven inflammatory disease of blood vessels, and both innate and
adaptive immune responses are involved in its development. The impact of B cells on …