As a new generation of artificial enzymes, nanozymes have the advantages of high catalytic
activity, good stability, low cost, and other unique properties of nanomaterials. Due to their …

Taurine is a fundamental mediator of homeostasis that exerts multiple roles to confer
protection against oxidant stress. The development of hypertension, muscle/neuro‑​ …

Hepatic ischemia reperfusion injury (IRI) is not only a pathophysiological process involving
the liver, but also a complex systemic process affecting multiple tissues and organs. Hepatic …

Liver fibrosis represents a health problem with significant morbidity and mortality that affects
100 million people worldwide. It is a final pathway to several chronic liver diseases and is …

The use of many halogenated alkanes such as carbon tetrachloride (CCl4), chloroform
(CHCl3) or iodoform (CHI3), has been banned or severely restricted because of their distinct …

This review addresses recent advances in specific mechanisms of hepatotoxicity. Because
of its unique metabolism and relationship to the gastrointestinal tract, the liver is an important …

Hayes' Principles and Methods of Toxicology has long been established as a reliable and
informative reference for the concepts, methodologies, and assessments integral to …

The complex functions of the liver in biosynthesis, metabolism, clearance, and host defense
are tightly dependent on an adequate microcirculation. To guarantee hepatic homeostasis …

Liver cell death induced by stresses such as ischemia‐reperfusion, cholestasis and drug
toxicity can trigger a sterile inflammatory response with activation of innate immune cells …

It is only during the last decade that the functions of sinusoidal endothelial cells, Kupffer
cells, hepatic stellate cells, pit cells and other intrahepatic lymphocytes have been better …