Tumorigenesis mechanisms found in hereditary renal cell carcinoma: a review
Renal cell carcinoma is a heterogenous cancer composed of an increasing number of
unique subtypes each with their own cellular and tumor behavior. The study of hereditary …
unique subtypes each with their own cellular and tumor behavior. The study of hereditary …
Understanding the tumor immune microenvironment in renal cell carcinoma
DD Shapiro, B Dolan, IA Laklouk, S Rassi, T Lozar… - Cancers, 2023 - mdpi.com
Simple Summary Over the last decade there has been a significant increase in the number
of therapies that activate the host's immune system to target and eliminate renal cell …
of therapies that activate the host's immune system to target and eliminate renal cell …
Currently Used Methods to Evaluate the Efficacy of Therapeutic Drugs and Kidney Safety
HJ Huang, CL Chou, TT Sandar, WC Liu, HC Yang… - Biomolecules, 2023 - mdpi.com
Kidney diseases with kidney failure or damage, such as chronic kidney disease (CKD) and
acute kidney injury (AKI), are common clinical problems worldwide and have rapidly …
acute kidney injury (AKI), are common clinical problems worldwide and have rapidly …
Integrating tumor and healthy epithelium in a micro-physiology multi-compartment approach to study renal cell carcinoma pathophysiology
M Somova, S Simm, A Padmyastuti, J Ehrhardt… - Scientific Reports, 2024 - nature.com
The advent of micro-physiological systems (MPS) in biomedical research has enabled the
introduction of more complex and relevant physiological into in vitro models. The recreation …
introduction of more complex and relevant physiological into in vitro models. The recreation …
Metabolic alterations in hereditary and sporadic renal cell carcinoma
NJ Coffey, MC Simon - Nature Reviews Nephrology, 2024 - nature.com
Kidney cancer is the seventh leading cause of cancer in the world, and its incidence is on
the rise. Renal cell carcinoma (RCC) is the most common form and is a heterogeneous …
the rise. Renal cell carcinoma (RCC) is the most common form and is a heterogeneous …
Circulating tumor cells as biomarkers for renal cell carcinoma: ready for prime time?
A Couto-Cunha, C Jerónimo, R Henrique - Cancers, 2022 - mdpi.com
Simple Summary Renal cell carcinoma (RCC) is the most common form of kidney cancer,
characterized by silent progression at early stages, heterogeneous behavior and resistance …
characterized by silent progression at early stages, heterogeneous behavior and resistance …
Microphysiological systems as models for immunologically 'cold'tumors
D Gaebler, SJ Hachey, CCW Hughes - Frontiers in Cell and …, 2024 - frontiersin.org
The tumor microenvironment (TME) is a diverse milieu of cells including cancerous and non-
cancerous cells such as fibroblasts, pericytes, endothelial cells and immune cells. The …
cancerous cells such as fibroblasts, pericytes, endothelial cells and immune cells. The …
The 5th Kidney Cancer Research Summit: Research Accelerating Cures for Renal Cell Carcinoma in 2023
Abstract The 5th Kidney Cancer Research Summit was a hybrid event hosted in Boston, MA
in July 2023. As in previous editions, the conference attracted a wide representation of …
in July 2023. As in previous editions, the conference attracted a wide representation of …
[HTML][HTML] Enhancing glomeruli segmentation through cross-species pre-training
The importance of kidney biopsy, a medical procedure in which a small tissue sample is
extracted from the kidney for examination, is increasing due to the rising incidence of kidney …
extracted from the kidney for examination, is increasing due to the rising incidence of kidney …
Mathematical and Machine Learning Models of Renal Cell Carcinoma: A Review
This review explores the multifaceted landscape of renal cell carcinoma (RCC) by delving
into both mechanistic and machine learning models. While machine learning models …
into both mechanistic and machine learning models. While machine learning models …