Ancient DNA study reveals HLA susceptibility locus for leprosy in medieval Europeans
B Krause-Kyora, M Nutsua, L Boehme, F Pierini… - Nature …, 2018 - nature.com
Leprosy, a chronic infectious disease caused by Mycobacterium leprae (M. leprae), was very
common in Europe till the 16th century. Here, we perform an ancient DNA study on medieval …
common in Europe till the 16th century. Here, we perform an ancient DNA study on medieval …
Pan-genome analysis of ancient and modern Salmonella enterica demonstrates genomic stability of the invasive para C lineage for millennia
Salmonella enterica serovar Paratyphi C causes enteric (paratyphoid) fever in humans. Its
presentation can range from asymptomatic infections of the blood stream to gastrointestinal …
presentation can range from asymptomatic infections of the blood stream to gastrointestinal …
Genome-wide data from medieval German Jews show that the Ashkenazi founder event pre-dated the 14th century
We report genome-wide data from 33 Ashkenazi Jews (AJ), dated to the 14 th century,
obtained following a salvage excavation at the medieval Jewish cemetery of Erfurt …
obtained following a salvage excavation at the medieval Jewish cemetery of Erfurt …
Ancient Plasmodium genomes shed light on the history of human malaria
M Michel, E Skourtanioti, F Pierini, EK Guevara… - Nature, 2024 - nature.com
Malaria-causing protozoa of the genus Plasmodium have exerted one of the strongest
selective pressures on the human genome, and resistance alleles provide biomolecular …
selective pressures on the human genome, and resistance alleles provide biomolecular …
Multi-omic detection of Mycobacterium leprae in archaeological human dental calculus
AK Fotakis, SD Denham, M Mackie… - … of the Royal …, 2020 - royalsocietypublishing.org
Mineralized dental plaque (calculus) has proven to be an excellent source of ancient
biomolecules. Here we present a Mycobacterium leprae genome (6.6-fold), the causative …
biomolecules. Here we present a Mycobacterium leprae genome (6.6-fold), the causative …
A seventeenth-century Mycobacterium tuberculosis genome supports a Neolithic emergence of the Mycobacterium tuberculosis complex
Background Although tuberculosis accounts for the highest mortality from a bacterial
infection on a global scale, questions persist regarding its origin. One hypothesis based on …
infection on a global scale, questions persist regarding its origin. One hypothesis based on …
Ancient viral genomes reveal introduction of human pathogenic viruses into Mexico during the transatlantic slave trade
AA Guzmán-Solís, V Villa-Islas, MJ Bravo-López… - Elife, 2021 - elifesciences.org
After the European colonization of the Americas, there was a dramatic population collapse of
the Indigenous inhabitants caused in part by the introduction of new pathogens. Although …
the Indigenous inhabitants caused in part by the introduction of new pathogens. Although …
Paleomicrobiology: diagnosis and evolution of ancient pathogens
The last century has witnessed progress in the study of ancient infectious disease from
purely medical descriptions of past ailments to dynamic interpretations of past population …
purely medical descriptions of past ailments to dynamic interpretations of past population …
Shotgun metagenomic analysis reveals the prevalence of antibiotic resistance genes and mobile genetic elements in full scale hospital wastewater treatment plants
Wastewater treatment plants are considered as hotspots of emerging antimicrobial genes
and mobile genetic elements. We used a shotgun metagenomic approach to examine the …
and mobile genetic elements. We used a shotgun metagenomic approach to examine the …
[HTML][HTML] Origin and health status of first-generation Africans from early colonial Mexico
The forced relocation of several thousand Africans during Mexico's historic period has so far
been documented mostly through archival sources, which provide only sparse detail on their …
been documented mostly through archival sources, which provide only sparse detail on their …