[HTML][HTML] Mechanisms of obesity-and diabetes mellitus-related pancreatic carcinogenesis: A comprehensive and systematic review

R Ruze, J Song, X Yin, Y Chen, R Xu… - … and Targeted Therapy, 2023 - nature.com
Research on obesity-and diabetes mellitus (DM)-related carcinogenesis has expanded
exponentially since these two diseases were recognized as important risk factors for …

[HTML][HTML] The role of cow's milk consumption in breast cancer initiation and progression

BC Melnik, SM John, P Carrera-Bastos… - Current Nutrition …, 2023 - Springer
Abstract Purpose of Review This review evaluates cow milk's impact on breast
carcinogenesis by linking recent epidemiological evidence and new insights into the …

Rna M6a Methylation Regulates Glycolysis of Beige Fat and Contributes to Systemic Metabolic Homeostasis

Y Li, Y Zhang, T Zhang, X Ping, D Wang… - Advanced …, 2023 - Wiley Online Library
Abstract N6‐methyladenosine (m6A) modification has been implicated in the progression of
obesity and metabolic diseases. However, its impact on beige fat biology is not well …

[HTML][HTML] RNA modification: mechanisms and therapeutic targets

L Qiu, Q Jing, Y Li, J Han - Molecular Biomedicine, 2023 - Springer
RNA modifications are dynamic and reversible chemical modifications on substrate RNA
that are regulated by specific modifying enzymes. They play important roles in the regulation …

[HTML][HTML] Metabolo-epigenetic interplay provides targeted nutritional interventions in chronic diseases and ageing

M Gómez de Cedrón, R Moreno Palomares… - Frontiers in …, 2023 - frontiersin.org
Epigenetic modifications are chemical modifications that affect gene expression without
altering DNA sequences. In particular, epigenetic chemical modifications can occur on …

[HTML][HTML] The role of RNA modification in HIV-1 infection

S Wang, H Li, Z Lian, S Deng - International Journal of Molecular …, 2022 - mdpi.com
RNA plays an important role in biology, and more than 170 RNA modifications have been
identified so far. Post-transcriptional modification of RNA in cells plays a crucial role in the …

[HTML][HTML] Appraisal of gene-environment interactions in GWAS for evidence-based precision nutrition implementation

R San-Cristobal, J de Toro-Martín, MC Vohl - Current Nutrition Reports, 2022 - Springer
Abstract Purpose of Review This review aims to analyse the currently reported gene-
environment (G× E) interactions in genome-wide association studies (GWAS), involving …

RNA m6A modification in prostate cancer: A new weapon for its diagnosis and therapy

Z Han, X Yi, J Li, T Zhang, D Liao, J You, J Ai - Biochimica et Biophysica …, 2023 - Elsevier
Prostate cancer (PCa) is the most common malignant tumor and the second leading cause
of cancer-related mortality in men worldwide. Despite significant advances in PCa therapy …

[HTML][HTML] N6-methyladenosine (m6A) in cancer therapeutic resistance: Potential mechanisms and clinical implications

D Wang, Y Zhang, Q Li, A Zhang, J Xu, Y Li, W Li… - Biomedicine & …, 2023 - Elsevier
Cancer therapy resistance (CTR) is the development of cancer resistance to multiple
therapeutic strategies, which severely affects clinical response and leads to cancer …

FTO overexpression expedites wound healing and alleviates depression in burn rats through facilitating keratinocyte migration and angiogenesis via mediating TFPI-2 …

Z Xu, X Zhu, S Mu, R Fan, B Wang, W Gao… - Molecular and Cellular …, 2024 - Springer
Burn injury is a serious traumatic injury that leads to severe physical and psychosocial
impairment. Wound healing after burn injury is a substantial challenge in medical …