In this study, the impact of gas composition (ie CO, CO 2 and H 2 partial pressures) on CO 2
utilization, growth, and acetate production was investigated in batch and continuous cultures …

Constraint-based modeling techniques have become a standard tool for the in silico
analysis of metabolic networks. To further improve their accuracy, recent methodological …

A great variety of software applications are now employed in the metabolic engineering field.
These applications have been created to support a wide range of experimental and analysis …

The cell density effect (ie, the drop in the specific productivity in the baculovirus‐insect cells
expression system when cells are infected at high cell densities) has been extensively …

Recent noteworthy advances in developing high‐performing microbial and mammalian
strains have enabled the sustainable production of bio‐economically valuable substances …

The identification of large regulatory and signalling networks involved in the control of
crucial cellular processes calls for proper modelling approaches. Indeed, models can help …

Background Microbial electrosynthesis is a novel approach that aims at shifting the cellular
metabolism towards electron-dense target products by extracellular electron supply. Many …

The concept of minimal cut sets (MCS) provides a flexible framework for analyzing
properties of metabolic networks and for computing metabolic intervention strategies. In …

Synthetic Biology offers qualitatively new perspectives on the benefits of industrially
harnessed biological processes. The ability to modify and reprogramme natural biology …

Background Heterologous microbial production of rare plant terpenoids of medicinal or
industrial interest is attracting more and more attention but terpenoid yields are still low …