BACKGROUND Subclinical hypothyroidism (SCH) and thyroid autoimmunity (TAI) are
associated with adverse pregnancy outcomes such as pregnancy loss and preterm birth …

In-vitro fertilisation has been done for nearly 30 years; in developed countries at least 1% of
births are from assisted reproductive therapies (ART). These children now represent a …

Background The transfer of fresh embryos is generally preferred over the transfer of frozen
embryos for in vitro fertilization (IVF), but some evidence suggests that frozen-embryo …

OBJECTIVE: To compare multiple-cell trophectoderm biopsy for preimplantation genetic
diagnosis (PGD) from day-5 blastocysts with previously published experience with day-3 …

OBJECTIVE: To give an overview of currently used investigations and treatments offered to
women with recurrent pregnancy loss (RPL) and, from an evidence-based point of view, to …

In recent years, the growing use of ART (assisted reproductive techniques) has led to a
progressive improvement of protocols; embryo freezing is certainly one of the most important …

Background Family planning is an important consideration for women with multiple sclerosis
(MS), who are often diagnosed during their reproductive years. Currently, limited data are …

Background The risk of spontaneous abortion in patients with polycystic ovary syndrome
(PCOS) undergoing assisted reproductive treatment (ART) is higher than that in patients …

Developmental pathways in humans and other organisms are buffered against changes in
genotype and environment. Therefore, it should not come as a surprise that most of the …

OBJECTIVE: To evaluate the effect of pregestational metformin administration on abortion
risk in polycystic ovary syndrome (PCOS) patients. DESIGN: Systematic review and meta …