[HTML][HTML] Hypoxia contributes to melanoma heterogeneity by triggering HIF1α-dependent phenotype switching
We have previously reported a model for melanoma progression in which oscillation
between melanoma cell phenotypes characterized by invasion or proliferation is …
between melanoma cell phenotypes characterized by invasion or proliferation is …
[HTML][HTML] Oxygen enhanced optoacoustic tomography (OE-OT) reveals vascular dynamics in murine models of prostate cancer
MR Tomaszewski, IQ Gonzalez, JPB O'Connor… - Theranostics, 2017 - ncbi.nlm.nih.gov
Poor oxygenation of solid tumours has been linked with resistance to chemo-and radio-
therapy and poor patient outcomes, hence non-invasive imaging of oxygen supply and …
therapy and poor patient outcomes, hence non-invasive imaging of oxygen supply and …
Radiotherapy resistance: identifying universal biomarkers for various human cancers
I Larionova, M Rakina, E Ivanyuk, Y Trushchuk… - Journal of cancer …, 2022 - Springer
Radiotherapy (RT) is considered as a standard in the treatment of most solid cancers,
including glioblastoma, lung, breast, rectal, prostate, colorectal, cervical, esophageal, and …
including glioblastoma, lung, breast, rectal, prostate, colorectal, cervical, esophageal, and …
Review of ultrasound image guidance in external beam radiotherapy part II: intra-fraction motion management and novel applications
T O'Shea, J Bamber, D Fontanarosa… - Physics in medicine …, 2016 - iopscience.iop.org
Imaging has become an essential tool in modern radiotherapy (RT), being used to plan dose
delivery prior to treatment and verify target position before and during treatment. Ultrasound …
delivery prior to treatment and verify target position before and during treatment. Ultrasound …
NRP1 promotes prostate cancer progression via modulating EGFR-dependent AKT pathway activation
P Zhang, L Chen, F Zhou, Z He, G Wang, Y Luo - Cell Death & Disease, 2023 - nature.com
Prostate cancer (PCa) is the most common malignant tumor with a high global incidence in
males. The mechanism underlying PCa progression is still not clear. This study observed …
males. The mechanism underlying PCa progression is still not clear. This study observed …
AMP-activated protein kinase promotes human prostate cancer cell growth and survival
HU Park, S Suy, M Danner, V Dailey, Y Zhang… - Molecular cancer …, 2009 - AACR
The molecular mechanisms underlying the development and progression of prostate cancer
are poorly understood. AMP-activated protein kinase (AMPK) is a serine-threonine kinase …
are poorly understood. AMP-activated protein kinase (AMPK) is a serine-threonine kinase …
Hypoxia-induced signaling promotes prostate cancer progression: exosomes role as messenger of hypoxic response in tumor microenvironment
G Deep, GK Panigrahi - Critical Reviews™ in Oncogenesis, 2015 - dl.begellhouse.com
Prostate cancer (PCA) is the leading malignancy in men and the second leading cause of
cancer-related deaths. Hypoxia (low O 2 condition) is considered an early event in prostate …
cancer-related deaths. Hypoxia (low O 2 condition) is considered an early event in prostate …
Targeting hypoxic tumour cells to overcome metastasis
KL Bennewith, S Dedhar - BMC cancer, 2011 - Springer
The microenvironment within solid tumours can influence the metastatic dissemination of
tumour cells, and recent evidence suggests that poorly oxygenated (hypoxic) cells in primary …
tumour cells, and recent evidence suggests that poorly oxygenated (hypoxic) cells in primary …
Oxygen-enhanced MRI is feasible, repeatable, and detects radiotherapy-induced change in hypoxia in Xenograft models and in patients with non–small cell lung …
A Salem, RA Little, A Latif, AK Featherstone… - Clinical Cancer …, 2019 - AACR
Purpose: Hypoxia is associated with poor prognosis and is predictive of poor response to
cancer treatments, including radiotherapy. Developing noninvasive biomarkers that both …
cancer treatments, including radiotherapy. Developing noninvasive biomarkers that both …
Aberrant lipid metabolism promotes prostate cancer: role in cell survival under hypoxia and extracellular vesicles biogenesis
G Deep, IR Schlaepfer - International Journal of Molecular Sciences, 2016 - mdpi.com
Prostate cancer (PCa) is the leading malignancy among men in United States. Recent
studies have focused on the identification of novel metabolic characteristics of PCa, aimed at …
studies have focused on the identification of novel metabolic characteristics of PCa, aimed at …