In search of new therapeutic targets and strategies for heart failure: recent advances in basic science

AM Shah, DL Mann - The Lancet, 2011 - thelancet.com
Chronic heart failure continues to impose a substantial health-care burden, despite recent
treatment advances. The key pathophysiological process that ultimately leads to chronic …

Effect of QRS morphology on clinical event reduction with cardiac resynchronization therapy: meta-analysis of randomized controlled trials

I Sipahi, JC Chou, M Hyden, DY Rowland… - American heart …, 2012 - Elsevier
BACKGROUND: Cardiac resynchronization therapy (CRT) is effective in reducing clinical
events in systolic heart failure patients with a wide QRS. Previous retrospective studies …

2013 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy: the Task Force on cardiac pacing and resynchronization therapy of the European …

Authors/Task Force Members, M Brignole… - European heart …, 2013 - academic.oup.com
The content of these European Society of Cardiology (ESC) Guidelines has been published
for personal and educational use only. No commercial use is authorized. No part of the ESC …

Primary results from the SmartDelay determined AV optimization: a comparison to other AV delay methods used in cardiac resynchronization therapy (SMART-AV) trial …

KA Ellenbogen, MR Gold, TE Meyer… - Circulation, 2010 - Am Heart Assoc
Background One variable that may influence cardiac resynchronization therapy response is
the programmed atrioventricular (AV) delay. The SmartDelay Determined AV Optimization: A …

Effect of cardiac resynchronization therapy on reverse remodeling and relation to outcome: multicenter automatic defibrillator implantation trial: cardiac …

SD Solomon, E Foster, M Bourgoun, A Shah, E Viloria… - Circulation, 2010 - Am Heart Assoc
Background—Cardiac resynchronization therapy (CRT) plus implantation of an implantable
cardioverter defibrillator (ICD) reduced the risk of death or heart failure event in patients with …

Clinical outcomes with synchronized left ventricular pacing: analysis of the adaptive CRT trial

D Birnie, B Lemke, K Aonuma, H Krum, KLF Lee… - Heart Rhythm, 2013 - Elsevier
Background Acute studies have suggested that left ventricular pacing (LVP) may have
benefits over biventricular pacing (BVP). The adaptive cardiac resynchronization therapy …

Meta-analysis: cardiac resynchronization therapy for patients with less symptomatic heart failure

NS Al-Majed, FA McAlister, JA Bakal… - Annals of internal …, 2011 - acpjournals.org
Background: Cardiac resynchronization therapy (CRT) reduces morbidity and mortality in
patients with advanced symptoms of heart failure. Purpose: To assess the benefits and …

Left ventricular versus simultaneous biventricular pacing in patients with heart failure and a QRS complex≥ 120 milliseconds

B Thibault, A Ducharme, F Harel, M White, E O'Meara… - Circulation, 2011 - Am Heart Assoc
Background—Left ventricular (LV) pacing alone may theoretically avoid deleterious effects
of right ventricular pacing. Methods and Results—In a multicenter, double-blind, crossover …

Incidence, determinants, and prognostic value of reverse left ventricular remodelling after primary percutaneous coronary intervention: results of the Acute Myocardial …

S Funaro, G La Torre, M Madonna… - European heart …, 2009 - academic.oup.com
Aims Few data are available on the extent and prognostic value of reverse left ventricular
remodelling (r-LVR) after ST-elevation acute myocardial infarction (STEMI). We sought to …

A randomized double-blind comparison of biventricular versus left ventricular stimulation for cardiac resynchronization therapy: the Biventricular versus Left …

G Boriani, W Kranig, E Donal, L Calo, M Casella… - American heart …, 2010 - Elsevier
BACKGROUND: Biventricular (BiV) stimulation is the preferred means of delivering cardiac
resynchronization therapy (CRT), although left ventricular (LV)–only stimulation might be as …