Development and optimization of microfluidic assisted manufacturing process to produce PLGA nanoparticles

E Chiesa, M Bellotti, A Caimi, B Conti, R Dorati… - International Journal of …, 2022 - Elsevier
Nanomedicine consists in the application of nanotechnology in medicine to revolutionize the
healthcare sector through transformative new diagnostic and therapeutic tools. In this field …

Analytical approaches for the characterization and quantification of nanoparticles in food and beverages

M Mattarozzi, M Suman, C Cascio, D Calestani… - Analytical and …, 2017 - Springer
Estimating consumer exposure to nanomaterials (NMs) in food products and predicting their
toxicological properties are necessary steps in the assessment of the risks of this …

How to concentrate nanoparticles and avoid aggregation?

C Vauthier, B Cabane, D Labarre - European Journal of Pharmaceutics and …, 2008 - Elsevier
Most of the methods that are used to produce pharmaceutical suspensions of nanoparticles
for drug-targeting yield suspensions having a low content in drug carriers. This can be a …

Tangential flow filtration technique: An overview on nanomedicine applications

T Musumeci, A Leonardi, A Bonaccorso… - Pharmaceutical …, 2018 - ingentaconnect.com
Purification is a key step for different types of approaches, ranging from food, biotechnology
to pharmaceutical fields. In biotechnology, tangential flow filtration (TFF) allows obtaining the …

[HTML][HTML] Single-pass tangential flow filtration (SPTFF) of nanoparticles: Achieving sustainable operation with dilute colloidal suspensions for gene therapy applications

AS Chaubal, AL Zydney - Membranes, 2023 - mdpi.com
Recent approval of several viral-vector-based therapeutics has led to renewed interest in the
development of more efficient bioprocessing strategies for gene therapy products. Single …

SPIONs and magnetic hybrid materials: Synthesis, toxicology and biomedical applications

RP Friedrich, C Janko, H Unterweger… - Physical Sciences …, 2023 - degruyter.com
In the past decades, a wide variety of different superparamagnetic iron oxide nanoparticles
(SPIONs) have been synthesized. Due to their unique properties, such as big surface-to …

Nonspherical nanoparticle shape stability is affected by complex manufacturing aspects: Its implications for drug delivery and targeting

BM Haryadi, D Hafner, I Amin… - Advanced …, 2019 - Wiley Online Library
The shape of nanoparticles is known recently as an important design parameter influencing
considerably the fate of nanoparticles with and in biological systems. Several manufacturing …

Scalable manufacturing processes for solid lipid nanoparticles

G Anderluzzi, G Lou, Y Su… - Pharmaceutical …, 2019 - ingentaconnect.com
Background: Solid lipid nanoparticles offer a range of advantages as delivery systems but
they are limited by effective manufacturing processes. Objective: In this study, we outline a …

A new design for obtaining of white zein micro-and nanoparticles powder: Antisolvent-dialysis method

F Rodríguez-Félix, CL Del-Toro-Sánchez… - Food science and …, 2020 - Springer
The objective of this work was propose antisolvent-dialysis as a new, easy, one-step and
reproducible method for obtaining white zein micro-and nanoparticles powder. Firstly, the …

Rational design of gold nanoparticle toxicology assays: a question of exposure scenario, dose and experimental setup

U Taylor, C Rehbock, C Streich, D Rath… - Nanomedicine, 2014 - Taylor & Francis
Many studies have evaluated the toxicity of gold nanoparticles, although reliable predictions
based on these results are rare. In order to overcome this problem, this article highlights …