The metabolic disposition of norgestrel in female rhesus monkeys.

SF Sisenwine, HB Kimmel, AL Liu… - Drug Metabolism and …, 1979 - ASPET
Following single intragastric doses of d-and dl-[24C] norgestrel (Ng), rhesus monkeys
excreted 29.5+/-2.0 (SE) and 52.6+/-5.4% of the administered radioactivity in urine. Fecal …

Mechanism of action of gestagens

BM Landgren - International Journal of Gynecology & Obstetrics, 1990 - Elsevier
In the mid-1950s it was shown that ovulation can be inhibited by oral administration of
progesterone or of synthetic progestogens such as norethynodrel. The idea that …

Injectable depot contraceptives on d-norgestrel basis II. Clinical pharmacokinetic studies with d-norgestrel undecylate in women

J Spona, E Weiner, B Nieuweboer, M Hümpel… - Contraception, 1977 - Elsevier
The effect of a single intramuscular injection of 100 mg of d-norgestrel 17β-undecylate was
investigated in 8 women. Levels of radioimmunoassayable serum progesterone, 17β …

Bleeding and ovulation control with use of a small contraceptive vaginal ring releasing levonorgestrel and estradiol

J Toivonen, P Lähteenmäki, T Luukkainen - Contraception, 1979 - Elsevier
Levonorgestrel and estradiol releasing contraceptive vaginal rings (CVR) with an outer
diameter of 50 mm were used by twenty women. The treatment was given in three-week …

The use of a contraceptive vaginal ring governed by the pattern of individual uterine bleeding

J Toivonen, P Lähteenmäki, T Luukkainen - Contraception, 1979 - Elsevier
Contraceptive vaginal rings (CVR) releasing levonorgestrel and estradiol were used for
contraceptive purposes in eight women. They were instructed to remove the CVR for five …

Determination of plasma concentrations of d-norgestrel during a one year follow-up in women with a d-norgestrel-releasing IUD

CG Nilsson, T Luukainen, P Lähteenmäki - Contraception, 1978 - Elsevier
Eight healthy women had a d-norgestrel-releasing intrauterine device inserted
postmenstrually and maintained in the uterine cavity for a one year period. Plasma …

Injectable depot contraceptives on d-norgestrel basis I. Pharmacokinetic studies in dog and baboons

M Hümpel, G Kühne, PE Schulze, U Speck - Contraception, 1977 - Elsevier
Five d-norgestrel 17β-fatty acids with chain lengths of 6–16 carbon atoms were dissolved in
castor oil/benzyl benzoate (6: 4, v/v) and administered intramuscularly to dogs. The kinetics …

Release of contraceptive steroids from sustained release dosage forms and resulting plasma levels

HA Nash, DN Robertson, TM Jackanicz - Contraception, 1978 - Elsevier
The correlations of plasma levels of levonorgestrel, megestrol acetate and norgestrienone
with the doses delivered from subdermal implants and contraceptive rings have been …

Clinical and endocrinologic study of continuous levonorgestrel administration from subcutaneous solid polydimethylsiloxane rods

S Roy, F Stanczyk, DR Mishell Jr, M Lumkin… - Contraception, 1980 - Elsevier
Three solid polydimethylsiloxane (Silastic®) rods containing levonorgestrel were inserted
into the subcutaneous tissue of the volar aspect of the forearm of 8 women. Serum samples …

[HTML][HTML] Pharmacokinetics and pharmacodynamics of a combined oral contraceptive and a generic combined formulation antiretroviral in Malawi

GS Stuart, A Moses, A Corbett, G Phiri… - Journal of acquired …, 2011 - ncbi.nlm.nih.gov
Pharmacokinetics and Pharmacodynamics of a Combined Oral Contraceptive and a Generic
Combined Formulation Antiretroviral in Malawi - PMC Back to Top Skip to main content NIH …