Randomized, placebo controlled phase I trial of safety, pharmacokinetics, pharmacodynamics and acceptability of tenofovir and tenofovir plus levonorgestrel vaginal …
AR Thurman, JL Schwartz, V Brache, MR Clark… - PloS one, 2018 - journals.plos.org
To prevent the global health burdens of human immunodeficiency virus [HIV] and
unintended/mistimed pregnancies, we developed an intravaginal ring [IVR] that delivers …
unintended/mistimed pregnancies, we developed an intravaginal ring [IVR] that delivers …
[HTML][HTML] Serum and peritoneal fluid levels of levonorgestrel in women with endometriosis who were treated with an intrauterine contraceptive device containing …
FB Lockhat, JE Emembolu, JC Konje - Fertility and sterility, 2005 - Elsevier
OBJECTIVE: To determine and compare levels of levonorgestrel (Lng) in serum and
peritoneal fluid (PF) of patients on the Lng intrauterine system Mirena®(Schering Health …
peritoneal fluid (PF) of patients on the Lng intrauterine system Mirena®(Schering Health …
Ovarian suppression in normal-weight and obese women during oral contraceptive use: a randomized controlled trial
CL Westhoff, AH Torgal, ER Mayeda… - Obstetrics & …, 2010 - journals.lww.com
OBJECTIVE: To assess ovarian suppression during oral contraceptive pill (OCP) use among
normal-weight and obese women using two OCP doses. METHODS: This was a …
normal-weight and obese women using two OCP doses. METHODS: This was a …
Sustained intrauterine release of levonorgestrel over five years
CG Nilsson, PLA Lahteenmaki, T Luukkainen… - Fertility and sterility, 1986 - Elsevier
Two models of levonorgestrel-releasing intrauterine devices were studied. Model A was
designed to deliver 20 μg/day, and model B was designed to deliver 30 μglday. Plasma …
designed to deliver 20 μg/day, and model B was designed to deliver 30 μglday. Plasma …
Carbamazepine coadministration with an oral contraceptive: effects on steroid pharmacokinetics, ovulation, and bleeding
AR Davis, CL Westhoff, FZ Stanczyk - Epilepsia, 2011 - Wiley Online Library
Summary Purpose: Antiepileptic drugs (AEDs) are widely used in reproductive‐age women.
The AED carbamazepine (CBZ) induces the hepatic cytochrome P450 system, thereby …
The AED carbamazepine (CBZ) induces the hepatic cytochrome P450 system, thereby …
Contraception by NORPLANTR subdermal capsules is not reliable in epileptic patients on anticonvulsant treatment
M Haukkamaa - Contraception, 1986 - Elsevier
The contraceptive efficacy of progestin-only contraception was studied in epileptic patients
using NORPLANT R subdermal capsules. The effect of anticonvulsants on levonorgestrel …
using NORPLANT R subdermal capsules. The effect of anticonvulsants on levonorgestrel …
Plasma levels of d-norgestrel after oral administration
E Weiner, A Victor, EDB Johansson - Contraception, 1976 - Elsevier
Peripheral plasma levels of d-norgestrel were determined by radioimmunoassay in five
women after oral administration of 30, 250 and 1000 μg d-norgestrel. Peak levels of d …
women after oral administration of 30, 250 and 1000 μg d-norgestrel. Peak levels of d …
Levonorgestrel plasma concentrations and hormone profiles after insertion and after one year of treatment with a levonorgestrel-IUD
CG Nilsson, P Lähteenmäki, T Luukkainen - Contraception, 1980 - Elsevier
Plasma concentrations of levonorgestrel, progesterone, estradiol, FSH and LH were
measured in seven volunteers who had a levonorgestrel-releasing IUD inserted …
measured in seven volunteers who had a levonorgestrel-releasing IUD inserted …
An integrated population pharmacokinetic analysis to characterize levonorgestrel pharmacokinetics after different administration routes
I Reinecke, B Hofmann, E Mesic… - The Journal of …, 2018 - Wiley Online Library
To compare the pharmacokinetics (PK) of the progestin levonorgestrel for various routes of
administration, an integrated population PK analysis was performed. This analysis …
administration, an integrated population PK analysis was performed. This analysis …
Temporal changes in cervical mucus after insertion of the levonorgestrel-releasing intrauterine system
MF Natavio, DS Taylor, RA Lewis, P Blumenthal… - Contraception, 2013 - Elsevier
BACKGROUND: The major contraceptive action of the levonorgestrel-releasing intrauterine
system (LNG-IUS) is cervical mucus (CM) thickening, which prevents sperm penetration. No …
system (LNG-IUS) is cervical mucus (CM) thickening, which prevents sperm penetration. No …