Prevention and treatment of inflammatory arthritis with traditional Chinese medicine: underlying mechanisms based on cell and molecular targets

W Li, L Yu, W Li, G Ge, Y Ma, L Xiao, Y Qiao… - Ageing Research …, 2023 - Elsevier
Inflammatory arthritis, primarily including rheumatoid arthritis, osteoarthritis and ankylosing
spondylitis, is a group of chronic inflammatory diseases, whose general feature is joint …

Health effects of peptides extracted from deer antler

P Xia, D Liu, Y Jiao, Z Wang, X Chen, S Zheng, J Fang… - Nutrients, 2022 - mdpi.com
Deer antler is widely used as a nutraceutical in Asian countries. In the past decades, deer
antler peptides (DAPs) have received considerable attention because of their various …

Deer velvet antler extracts exert anti-inflammatory and anti-arthritic effects on human rheumatoid arthritis fibroblast-like synoviocytes and distinct mouse arthritis

WJ Cheng, HT Yang, CC Chiang, KH Lai… - The American Journal …, 2022 - World Scientific
Rheumatoid arthritis (RA) is a chronic autoimmune disease that causes joint deformity and
disability. Deer velvet antler (DA), a traditional Chinese medicine, has been used to treat …

[HTML][HTML] The Wnt signaling cascade in the pathogenesis of osteoarthritis and related promising treatment strategies

J Cheng, M Li, R Bai - Frontiers in Physiology, 2022 - frontiersin.org
Osteoarthritis (OA) is the most prevalent joint disease, characterized by the degradation of
articular cartilage, synovial inflammation, and changes in periarticular and subchondral …

VAP-PLGA microspheres (VAP-PLGA) promote adipose-derived stem cells (ADSCs)-induced wound healing in chronic skin ulcers in mice via PI3K/Akt/HIF-1α …

W Jiang, J Zhang, X Zhang, C Fan, J Huang - Bioengineered, 2021 - Taylor & Francis
Chronic skin ulcers are a primary global health problem. Velvet antler polypeptide (VAP)
regulates endothelial cell migration and angiogenic sprout. Adipose-derived stem cells …

Well-known polypeptides of deer antler velvet with key actives: modern pharmacological advances

H Sun, D Xiao, W Liu, X Li, Z Lin, Y Li… - … Archives of Pharmacology, 2024 - Springer
Deer antler velvet, with kidney tonifying, promoting the production of essence and blood,
strengthening tendons and bones, not only has a thousand-year medicinal history but also …

Hypoxia-treated adipose mesenchymal stem cell-derived exosomes attenuate lumbar facet joint osteoarthritis

J Zhao, Y Sun, X Sheng, J Xu, G Dai, R He, Y Jin… - Molecular …, 2023 - Springer
Background Lumbar facet joint osteoarthritis (LFJ OA) is a common disease, and there is still
a lack of effective disease-modifying therapies. Our aim was to determine the therapeutic …

Role of the Wnt pathway in the formation, development, and degeneration of intervertebral discs

ZL Wu, QQ Xie, TC Liu, X Yang, GZ Zhang… - Pathology-Research and …, 2021 - Elsevier
Intervertebral disc degeneration (IVDD) is an age-related degenerative disease that is the
main cause of low back pain. It seriously affects the quality of life of patients and places a …

[HTML][HTML] The separation of antler polypeptide and its effects on the proliferation and osteogenetic differentiation of bone marrow mesenchymal stem cells

P Wang, TF Sun, G Li, HM Zhang, F Liu… - Evidence-Based …, 2020 - hindawi.com
Background. Colla Cornus Cervi (CCC) has been used as a traditional Chinese medicine in
the treatment of osteoporosis and osteonecrosis of the femoral head. However, the …

Evidence-Based Complementary and Alternative Canine Orthopedic Medicine

E Miscioscia, J Repac - Veterinary Clinics: Small Animal …, 2022 - vetsmall.theclinics.com
Background Acupuncture is a 3000-year-old therapy in which small gauge needles are
placed at specific locations, or acupoints, in the body for a therapeutic effect. Acupoints …