Frontotemporal dementia refers to a group of neurodegenerative disorders characterized by
behaviour and language alterations and focal brain atrophy. Amyotrophic lateral sclerosis is …

Cell-based therapies are an emerging biopharmaceutical paradigm under investigation for
the treatment of a range of neurological disorders. Accumulating evidence is demonstrating …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease, involving
neuroinflammation and T cell infiltration in the central nervous system. However, the …

Background Dysregulation of the immune system in amyotrophic lateral sclerosis (ALS)
includes changes in T-cells composition and infiltration of T cells in the brain and spinal …

While inflammation may not be the cause of disease, it is well known that it contributes to
disease pathogenesis across a multitude of peripheral and central nervous system …

Growing evidence demonstrates a continuous interaction between the immune system, the
nerve and the muscle in neuromuscular disorders of different pathogenetic origins, such as …

Amyotrophic lateral sclerosis (ALS) is a fatal disease characterized by the degeneration and
death of motor neurons. Systemic neuroinflammation contributes to the pathogenesis of …

Amyotrophic lateral sclerosis is a fatal neurodegenerative disease causing upper and lower
motor neuron loss and currently no effective disease-modifying treatment is available. A …

Neurodegenerative disorders (ND) are progressive diseases of the nervous system, often
without resolutive therapy. They are characterized by a progressive impairment and loss of …

Regulatory T (Treg) cells interact with a variety of resident cells and infiltrated immune cells
in the central nervous system (CNS) to modulate neuroinflammation and …