Macroencapsulated bacteria for in vivo sensing and therapeutics
Engineered bacteria are increasingly recognized as sustained and intelligent sources for
sensing and therapeutics due to their unique capabilities such as in situ multiplication, tissue …
sensing and therapeutics due to their unique capabilities such as in situ multiplication, tissue …
The Gram-negative permeability barrier: tipping the balance of the in and the out
C Maher, KA Hassan - Mbio, 2023 - Am Soc Microbiol
Gram-negative bacteria are intrinsically resistant to many antibiotics, due in large part to the
permeability barrier formed by their cell envelope. The complex and synergistic interplay of …
permeability barrier formed by their cell envelope. The complex and synergistic interplay of …
In Situ Self‐Aggregation of Spirulina Skeleton Fibers Enhances the Efficacy of Anti‐Tumor Thermal Immunotherapy
YD Qi, ZN Zhuang, SM Zeng, Y Tang… - Advanced Functional …, 2024 - Wiley Online Library
The lack of broad‐spectrum tumor antigens, limited immunogenicity of antigens, and
immunosuppressive microenvironment in tumors have impeded the development of cancer …
immunosuppressive microenvironment in tumors have impeded the development of cancer …
Epitopes in the capsular polysaccharide and the porin OmpK36 receptors are required for bacteriophage infection of Klebsiella pneumoniae
RA Dunstan, RS Bamert, KS Tan, U Imbulgoda… - Cell Reports, 2023 - cell.com
To kill bacteria, bacteriophages (phages) must first bind to a receptor, triggering the release
of the phage DNA into the bacterial cell. Many bacteria secrete polysaccharides that had …
of the phage DNA into the bacterial cell. Many bacteria secrete polysaccharides that had …
Tunable force transduction through the Escherichia coli cell envelope
DP Williams-Jones, MN Webby… - Proceedings of the …, 2023 - National Acad Sciences
The outer membrane (OM) of Gram-negative bacteria is not energised and so processes
requiring a driving force must connect to energy-transduction systems in the inner …
requiring a driving force must connect to energy-transduction systems in the inner …
Streptomyces extracellular vesicles are a broad and permissive antimicrobial packaging and delivery system
KJ Meyer, JR Nodwell - Journal of Bacteriology, 2024 - Am Soc Microbiol
Streptomyces are the primary source of bioactive specialized metabolites used in research
and medicine, including many antimicrobials. These are presumed to be secreted and …
and medicine, including many antimicrobials. These are presumed to be secreted and …
Molecular Machines that Facilitate Bacterial Outer Membrane Protein Biogenesis
MT Doyle, HD Bernstein - Annual Review of Biochemistry, 2024 - annualreviews.org
Almost all outer membrane proteins (OMPs) in Gram-negative bacteria contain a β-barrel
domain that spans the outer membrane (OM). To reach the OM, OMPs must be translocated …
domain that spans the outer membrane (OM). To reach the OM, OMPs must be translocated …
Synergistic Approaches for Enhanced Light-Driven Hydrogen Production: A Membrane-Anchoring Protein-Engineered Biohybrid System with Dual Photosensitizers …
H Li, X Yu, Y Qin, T Jiang, J Wang, Z Cai, J Xu… - ACS Materials …, 2024 - ACS Publications
Sunlight-driven hydrogen production provides a sustainable solution for clean energy
generation. Despite their potential, extracellular photosensitized biohybrid systems are …
generation. Despite their potential, extracellular photosensitized biohybrid systems are …
Shigella flexneri Adapts to Niche-Specific Stresses through Modifications in Cell Envelope Composition and Decoration
Shigella flexneri is the primary causative agent of worldwide shigellosis. As the pathogen
transverses the distinct niches of the gastrointestinal tract it necessitates dynamic adaptation …
transverses the distinct niches of the gastrointestinal tract it necessitates dynamic adaptation …
The TAM, a Translocation and Assembly Module for protein assembly and potential conduit for phospholipid transfer
The assembly of β-barrel proteins into the bacterial outer membrane is an essential process
enabling the colonization of new environmental niches. The TAM was discovered as a …
enabling the colonization of new environmental niches. The TAM was discovered as a …