Promising traditional Chinese medicine for the treatment of cholestatic liver disease process (cholestasis, hepatitis, liver fibrosis, liver cirrhosis)

C Wei, J Qiu, Y Wu, Z Chen, Z Yu, Z Huang… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Cholestatic liver disease (CLD) is mainly characterized by
cholestasis. If not treated, it will deteriorate to cholestatic hepatitis, liver fibrosis, liver …

[HTML][HTML] Redox homeostasis in poultry: regulatory roles of NF-κB

PF Surai, II Kochish, MT Kidd - Antioxidants, 2021 - mdpi.com
Redox biology is a very quickly developing area of modern biological sciences, and roles of
redox homeostasis in health and disease have recently received tremendous attention …

[HTML][HTML] Ginsenoside Rg1 alleviates ANIT-induced cholestatic liver injury by inhibiting hepatic inflammation and oxidative stress via SIRT1 activation

Q Gao, G Li, Y Zu, Y Xu, C Wang, D Xiang, W He… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Ginseng (Panax ginseng CA Mey) is a common
traditional Chinese medicine used for anti-inflammation, treating colitis, type 2 diabetes …

γ-Mangostin abrogates AINT-induced cholestatic liver injury: Impact on Nrf2/NF-κB/NLRP3/Caspase-1/IL-1β/GSDMD signalling

MT Khayat, KA Mohammad, GA Mohamed… - Life Sciences, 2023 - Elsevier
Abstract γ-Mangostin (γ-MN) is one of the abundant xanthones separated from Garcinia
mangostana (Clusiaceae) pericarps that has been reported to have varied bioactivities such …

Sarmentosin promotes USP17 and regulates Nrf2-mediated mitophagy and cellular oxidative stress to alleviate APAP-induced acute liver failure

Z Jiang, X Yang, Y Han, J Li, C Hu, C Liu, W Xiao - Phytomedicine, 2022 - Elsevier
Background An overdose of acetaminophen (APAP), the main cause of acute liver failure
(ALF), induces oxidative stress that ultimately causes mitochondrial impairment and …

[HTML][HTML] Phytochemical constituents and biological activity of selected genera of family Crassulaceae: A review

MHA Hassan, A Elwekeel, A Moawad, N Afifi… - South African Journal of …, 2021 - Elsevier
Family Crassulaceae is a large family of dicotyledonous angiosperms characterized by its
unique form of photosynthesis. Although plants of this family are used mainly as ornamental …

Protective mechanism of Astragalus Polysaccharides against Cantharidin‐induced liver injury determined in vivo by liquid chromatography/mass spectrometry …

X Huang, W Tang, C Lin, Z Sa, M Xu… - Basic & Clinical …, 2021 - Wiley Online Library
Cantharidin (CTD) is a promising anticancer drug; however, its dosage is limited by
hepatotoxicity. We previously showed that Astragalus polysaccharides (APS) effectively …

[HTML][HTML] Medicinal herbs and their metabolites with biological potential to protect and combat liver toxicity and its disorders: A review

SI Shawon, RN Reyda, N Qais - Heliyon, 2024 - cell.com
The liver is an essential organ that helps the body with immunity, metabolism, and
detoxification, among other functions. Worldwide, liver illnesses are a leading cause of …

Structure elucidation of arabinogalactoglucan isolated from Sedum sarmentosum Bunge and its inhibition on hepatocellular carcinoma cells in vitro

X Zhang, C Bi, Q Chen, H Xu, H Shi, X Li - International Journal of …, 2021 - Elsevier
Sedum sarmentosum Bunge (SS) is clinically used as Chinese medicine for hepatitis related
diseases treatment. The purpose of this study was to explore the chemical structures of …

[HTML][HTML] Effects of Sedi Herba (Sedum sarmentosum) on attenuating cholestasis by the activation of the farnesoid x receptor (FXR)-mediated signaling

Z Liu, D Liu, M Chen, W Zong, X Zhou, F Meng… - Biomedicine & …, 2022 - Elsevier
Abstract Sedum sarmentosum (Sedi Herba) has traditionally been used to treat jaundice and
various types of liver disease. This study aimed to clarify the anti-cholestatic efficacy and the …