[HTML][HTML] Viral proteases as therapeutic targets

T Majerová, J Konvalinka - Molecular aspects of medicine, 2022 - Elsevier
Some medically important viruses―including retroviruses, flaviviruses, coronaviruses, and
herpesviruses―code for a protease, which is indispensable for viral maturation and …

Precursors of viral proteases as distinct drug targets

T Majerová, P Novotný - Viruses, 2021 - mdpi.com
Viral proteases are indispensable for successful virion maturation, thus making them a
prominent drug target. Their enzyme activity is tightly spatiotemporally regulated by …

Exploiting the unique features of Zika and Dengue proteases for inhibitor design

T Majerová, P Novotný, E Krýsová, J Konvalinka - Biochimie, 2019 - Elsevier
Zika and Dengue viruses have attracted substantial attention from researchers in light of
recent outbreaks of Dengue fever and increases in cases of congenital microcephaly in …

Inhibitors of the M2 channel of influenza A virus

MD Duque, E Torres Costa… - Recent Advances in …, 2011 - diposit.ub.edu
Influenza is a highly contagious, major respiratory tract disease affecting millions of people
each year. At present, two classes of antivirals are available: the neuraminidase inhibitors …

Biofilms on rocks

M Hernández Mariné, M Roldán Molina - … Vallès, Chapter 1, p. 1-13., 2012 - diposit.ub.edu
Microorganisms group themselves into assemblies known as communities or biofilms, which
are associated with surfaces. A matrix of self-segregated polymeric substances enhances …